• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    Spectrum Solutions Collaborates with UCLA School of Dentistry

    Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization

    Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty

    Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

    FDA Clears 3D Acellular Dermal Matrix
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Fixing Face Mask Form and Function

    The Heart of the Matter: Trends in Cardiology

    Virtually the Same? The Challenges of Online Conferences

    Digital Health Delivers During a Year for the Ages

    Advanced Technology for Staking and Swaging Medical Plastics
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Element

    FUTEK Advanced Sensor Technology Inc.

    Concise Engineering

    MW Life Sciences

    Unicep
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Meeting Critical Ventilator Product Requirements Amid Pandemic

    Impact of COVID-19 on the Medtech Supply Chain

    Finding the Upside to a Challenging Year

    Preparing Your Design Controls for FDA Approval

    A 'Trial and Error' Approach to Micromolded Parts
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Creganna Medical, part of TE Connectivity

    PTI Engineered Plastics Inc.

    Unicep

    MW Life Sciences

    Qosina Corp.
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Company Developing a COVID-19 Severity Risk Test for U.S. Government

    The technology, known as host-response diagnostics, rapidly reads the immune system using multiple mRNA biomarkers and a machine learning algorithm.

    Company Developing a COVID-19 Severity Risk Test for U.S. Government
    Related CONTENT
    • High-Volume COVID Antigen Test Receives FDA EUA
    • Siemens Healthineers’ Laboratory-Based IL-6 Assay Receives EUA
    • BioSerenity Achieves FDA Clearance for Wearable Device System
    • Hologic to Buy Cancer Test Maker Biotheranostics for $230M
    • Thyroid Function Tests Market in India to Reach $125 Million in 2025
    Inflammatix11.04.20
    Inflammatix, a molecular diagnostics company, announced that the Defense Advanced Research Projects Agency (DARPA) has awarded the company up to $1.1 million for further development of a rapid diagnostic that reads the immune system to predict severe respiratory failure risk in COVID-19 patients. The diagnostic is being developed to help physicians make better hospital admission and resourcing decisions for COVID-19 patients at hospital presentation.
     
    The Inflammatix approach, known as host-response diagnostics, rapidly reads the immune system using multiple mRNA biomarkers and a machine learning algorithm. The company is developing other host-response diagnostic tests that identify the presence and type of infection (viral or bacterial), in addition to predicting the risk of severe disease, to enable physicians to make more informed decisions for patients with acute infection and sepsis.
     
    “We are grateful that DARPA has recognized the promise of our host-response approach to benefit COVID-19 patients and caregivers, and we look forward to accelerating development and availability of our CoVerityTM COVID-19 Severity Test as a result of this agreement,” said Inflammatix CEO and cofounder Tim Sweeney, M.D., Ph.D. “The 5-mRNA classifier for CoVerity was developed on a training set of more than 20 clinical studies and we intend to translate it into a rapid assay that can be used as a clinical tool to help triage patients after diagnosis with COVID-19. Improved triage has the potential to reduce morbidity and mortality while enabling hospitals to allocate resources more effectively.”
     
    The company’s host-response diagnostic approach for predicting COVID-19 severity risk was shown to be superior to clinical biomarkers, including IL-6, in a new study presented at the 2020 European Society of Clinical Microbiology and Infection Diseases (ESCMID) Conference on Coronavirus Disease (ECCVID).
     
    “While major progress has been made in developing rapid platforms to diagnose SARS-CoV-2 infection, predicting severity in COVID-19 patients remains an unmet medical need,” said Evangelos J. Giamarellos-Bourboulis, M.D., professor of Internal Medicine and Infectious Diseases at ATTIKON University General Hospital in Athens, Greece, chairman of the European Sepsis Alliance, president of the European Shock Society, and lead investigator for the study. “In this study, the host-response approach demonstrated very high accuracy for identifying severe disease in COVID-19 patients and outperformed clinical markers for risk stratification. Existing tools have shown limited accuracy in enabling us to confidently identify high-risk patients early who need close monitoring or discharge non-severe patients to recover at home.”
     
    In this prospective study of 97 patients with PCR-confirmed SARS-CoV-2 pneumonia and blood drawn on the day of admission at ATTIKON University General Hospital in Athens, Greece, CoVerity demonstrated an area under the receiver operating characteristic curve (AUROC) of 0.88 (95 percent CI 0.81-0.95) for identifying patients who developed respiratory failure or died, independent of age, while IL-6 had an AUROC of 0.73 (95 percent CI 0.62 - 0.85). The new classifier had the highest accuracy among all single biomarkers tested, including IL-6, procalcitonin, C-reactive protein, lactate, and SuPAR.
     
    This agreement is part of DARPA’s efforts to develop platform technologies that can be deployed safely and rapidly to provide the U.S. population with near-immediate protection against emerging infectious diseases and engineered biological weapons, even in cases when the pathogen or infectious agent is unknown.
     
    Suggested For You
    High-Volume COVID Antigen Test Receives FDA EUA High-Volume COVID Antigen Test Receives FDA EUA
    Siemens Healthineers’ Laboratory-Based IL-6 Assay Receives EUA Siemens Healthineers’ Laboratory-Based IL-6 Assay Receives EUA
    BioSerenity Achieves FDA Clearance for Wearable Device System BioSerenity Achieves FDA Clearance for Wearable Device System
    Hologic to Buy Cancer Test Maker Biotheranostics for $230M Hologic to Buy Cancer Test Maker Biotheranostics for $230M
    Thyroid Function Tests Market in India to Reach $125 Million in 2025 Thyroid Function Tests Market in India to Reach $125 Million in 2025
    EKF Introduces Accurate Quantitative COVID-19 Antibody Test Kit EKF Introduces Accurate Quantitative COVID-19 Antibody Test Kit
    Mologic COVID-19 Rapid Antigen Test Receives CE Mark Approval Mologic COVID-19 Rapid Antigen Test Receives CE Mark Approval
    FDA Authorizes Abbott FDA Authorizes Abbott's Rapid, $25 COVID-19 Test for At-Home Use
    FDA, EU Nods for POC Testing on Siemens Healthineers FDA, EU Nods for POC Testing on Siemens Healthineers' epoc NXS Host Mobile Computer
    BellaSeno Establishes High-Throughput Additive Manufacturing Facility for Resorbable Implants BellaSeno Establishes High-Throughput Additive Manufacturing Facility for Resorbable Implants
    Combo COVID-19, Flu Home Test Gains EUA Combo COVID-19, Flu Home Test Gains EUA
    CRISPR-Based COVID-19 Test Uses Smartphone Camera CRISPR-Based COVID-19 Test Uses Smartphone Camera
    Cytek Biosciences Completes Series D Funding Round Cytek Biosciences Completes Series D Funding Round
    Nissha Medical Technologies Nissha Medical Technologies
    NTK Cutting Tools USA NTK Cutting Tools USA

    Related Breaking News

    • Diagnostics
      Spectrum Solutions Collaborates with UCLA School of Dentistry

      Spectrum Solutions Collaborates with UCLA School of Dentistry

      Commences study on using saliva in early lung cancer detection and analysis.
      Charles Sternberg, Assistant Editor 01.27.21

    • Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization

      Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization

      Kwivik has developed a pipeline of products for certain respiratory, emergency medical, asthma, migraine/cluster headache, wound care, and skin care markets.
      Michael Barbella, Managing Editor 01.27.21

    • Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty

      Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty

      The procedure was carried out on an animal model late last year.
      Michael Barbella, Managing Editor 01.27.21


    • Cardiovascular | Surgical
      Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

      Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

      UBC Okanagan research could transform the current gold standard for heart valves.
      Sam Brusco, Associate Editor 01.27.21

    • FDA Clears 3D Acellular Dermal Matrix

      FDA Clears 3D Acellular Dermal Matrix

      The technology is supported by more than 150 peer-reviewed published articles.
      Michael Barbella, Managing Editor 01.27.21

    • Inogen to Undergo Leadership Transition

      Inogen to Undergo Leadership Transition

      Longtime BD exec Nabil Shabshab succeeds retiring Scott Wilkinson as president and CEO.
      Sam Brusco, Associate Editor 01.27.21


    • Asia-Pacific Advanced Wound Management Market to Undergo Robust Expansion

      Asia-Pacific Advanced Wound Management Market to Undergo Robust Expansion

      The market is being driven by a global aging population, increasing patient awareness levels, and rising disposable incomes.
      Michael Barbella, Managing Editor 01.27.21

    • Butterfly Network Appoints New Leader

      Butterfly Network Appoints New Leader

      Dr. Todd M. Fruchterman was most recently Flex’s group president of reliability solutions.
      Sam Brusco, Associate Editor 01.26.21

    • BD Names Chairman of Board

      BD Names Chairman of Board

      BD CEO and president, Tom Polen, joins the board.
      Charles Sternberg, Assistant Editor 01.26.21


    • Interplex Acquires OCP Group

      Interplex Acquires OCP Group

      The deal is a strategic investment in expanding Interplex’s Medical & Life Sciences product portfolio.
      Michael Barbella, Managing Editor 01.26.21

    • FDA Clears a Portable Hemodialysis System

      FDA Clears a Portable Hemodialysis System

      Quanta Dialysis Technologies' SC+ system became available in the U.K. last year.
      Michael Barbella, Managing Editor 01.26.21

    • Solid Growth Forecast for India

      Solid Growth Forecast for India's HER2 Amplification Tests Market

      Sector is expected to expand 7 percent annually over the next five years.
      Michael Barbella, Managing Editor 01.26.21


    • Diagnostics
      Abbott

      Abbott's Panbio Rapid COVID-19 Antigen Test Earns CE Mark for Two New Uses

      EU approves symptomatic screening and self-administered sample collection with nasal swab.
      Sam Brusco, Associate Editor 01.26.21

    • $30 Million in New Financing Secured by CathWorks

      $30 Million in New Financing Secured by CathWorks

      The company's FFRangio System is a non-invasive diagnostic technology that is used at the time of a routine angiography.
      Michael Barbella, Managing Editor 01.26.21

    • Cardiovascular
      Alleviant

      Alleviant's Transcatheter Tech Obtains Breakthrough Status

      The technology offers a no-implant interatrial shunt therapy for heart failure patients.
      Sam Brusco, Associate Editor 01.25.21


    Trending
    • Portable, Home-Use Device Quickly Measures Inflammation Levels
    • Henry Schein Buys Majority Interest In Prism Medical Products
    • Senseonics Forges Strategic Collaboration With Ascensia Diabetes Care
    • Top 10 Trends In The Medical Device And Equipment Industry
    • Cytotron Gains Breakthrough Status To Treat Breast, Liver, And Pancreatic Cancers
    Breaking News
    • Spectrum Solutions Collaborates with UCLA School of Dentistry
    • Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization
    • Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty
    • Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots
    • FDA Clears 3D Acellular Dermal Matrix
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Pharmaceutical Focus: A Look at Combination Products
    • The Printed World: Additive Manufacturing in Medtech
    • The Lost Year: 2020 Year in Review
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    PepsiCo and Beyond Meat Partner to Develop Plant-Based Protein
    New Study on Sage Extract Formula Suggests Memory Enhancement
    Omega-3s Evidenced to Reduce Low-Grade Inflammation in Elderly Men
    Coatings World

    Latest Breaking News From Coatings World

    Mayzo Makes 2 Appointments
    Mississippi Lime Company Announces New Director of Safety
    IFS Coatings Launches IFS Puroplaz PE20 Texture
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Spectrum Solutions Collaborates with UCLA School of Dentistry
    Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization
    Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Lilly, Vir, GSK Partner to Evaluate COVID Combo Therapies
    Novartis Invests in Credence MedSystems
    Ajinomoto Bio-Pharma, Humanigen Expand Manufacturing Agreement
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Coty to Shut Down Manufacturing Site in Cologne, Germany
    L’Occitane Files for Bankruptcy in U.S.
    Bésame Cosmetics Collaborates with Disney on Mary Poppins Collection
    Happi

    Latest Breaking News From Happi

    CLT Introduces Private Label Solid Air Freshener Cones
    The Florida Sunscreen Symposium Is Back!
    TFF Opens Nominations for 2021 Awards
    Ink World

    Latest Breaking News From Ink World

    Epson Partner Creates Label Applicators for Pharmaceutical Products
    Smurfit Kappa Sets New Sustainability Targets with Better Planet 2050
    Georgia-Pacific Acquires 3rd HP PageWide Corrugated Press to Expand Hummingbird Digital Printing
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Arjobex acquires MDV Group
    Fix-A-Form eyes global expansion
    McCracken Label installs Fujifilm water-wash plate system
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Nice-Pak Receives EPA Approval for Disinfecting Wipes
    Rockline to Invest $18 Million in Arkansas
    Essity’s Sales Negatively Impacted by Covid-19 Pandemic
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ChoiceSpine's Tiger Shark Cervical Spacer Earns Additional 510(k)
    FDA Green Lights Inspired Spine's Trident SI Joint Screw System
    FDA Clears Method to Extract Bone Measurements From X-Rays
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Osram Sees Jump in Profits in Preliminary 2020 Report
    LG Display Reports 4Q 2020 Results
    Xerox Releases 4Q, Full Year Results

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login