• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    MPO's 2023 Medtech Supply Chain Survey

    Exceeding Medical Device Extrusion Expectations

    Medical Device Micromolders Discuss the 'Minor Details'

    Superior Subtractive Solutions for Machining Medtech

    Assembly & Automation Experts Share Thoughts on Medtech Trends
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Regulatory
    Financial/Business
    Top News
    Former FDA Director Joins Greenleaf Health

    Alexander D’Amico Named Chief Financial Officer at CytoSorbents

    Moon Surgical Completes First U.S. Cases with Maestro System

    Senseonics Finishes 365-Day CGM Study Cohort

    Surface Solutions Group to Showcase GlideMed Coating at MD&M
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    MPO's 2023 Medtech Supply Chain Survey

    Exceeding Medical Device Extrusion Expectations

    Medical Device Micromolders Discuss the 'Minor Details'

    Superior Subtractive Solutions for Machining Medtech

    Assembly & Automation Experts Share Thoughts on Medtech Trends
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Back to School for Medical Device Cybersecurity Training

    Driving Clinical Trial Excellence to Help Study Teams Run a Faster Relay Race

    Medtech’s Supply Chain: From Disruption to Opportunity

    Are Medtech’s Mega-Deals Gone For Good?

    Will a Skilling Gap Hinder Organizational Readiness for Medtech’s New Age of AI?
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Medbio LLC

    Providence Enterprise USA Inc.

    NDH Medical Inc.

    Cirtec Medical

    Arthur G. Russell Co. Inc., The
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    How Wearables Are Changing the Way We Collect Real-World Data in Clinical Trials

    Could Medtech Ever Stop a Hospital Killer in Their Tracks?

    A One-Stop-Shop, Turnkey Solution Is Paramount for Success

    How Additive and Subtractive Manufacturing Are Revolutionizing the Medical Device Industry

    Medical Device Commercialization: It’s What, Not When, to Transfer to Manufacturing
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Medbio LLC

    Providence Enterprise USA Inc.

    NDH Medical Inc.

    Cirtec Medical

    Arthur G. Russell Co. Inc., The
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • eBook
    • Resources
    • Podcasts
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    SCIEX Debuts the ZenoTOF 7600 System

    System delivers new capabilities for life science research and biotherapeutic development.

    SCIEX Debuts the ZenoTOF 7600 System
    The ZenoTOF 7600 system. Image courtesy of Business Wire.
    Business Wire09.02.21
    SCIEX, a global leader in life science analytical technologies, has debuted the ZenoTOF 7600 system, a new accurate mass LC-MS/MS instrument. The new system enables scientists to identify, characterize and quantify molecules better than ever before by generating data that has been previously unattainable. This breakthrough will solve real analytical challenges and help advance the development of new precision diagnostics and biotherapeutics.
     
    “Only a step-change in innovation will meet the evermore ambitious goals of scientists around the world. This new platform and mindset in accurate mass has the power to change people’s perspective and profoundly impact lives,” said Joe Fox, president of SCIEX.
     
    The ZenoTOF 7600 system includes the proprietary Zeno trap and electron activated dissociation (EAD) fragmentation for the first time in a commercial instrument. Zeno trap pulsing overcomes the traditional duty cycle challenges of orthogonal TOF technology, delivering up to 20x the sensitivity and enabling the routine detection of important low-abundant molecules. In combination, tunable EAD fragmentation ensures novel structural information can be extracted and quantified from diverse compound types – a capability that is not possible by using high resolution alone.
     
    “The fact that we can now add alternative fragmentation to our existing workflows, and with higher sensitivity at the same time is really extraordinary. It's a real change in how data are generated and the biological insight we can get," said Matt Champion, associate professor, University of Notre Dame.
     
    Extraordinary sensitivity in combination with EAD fragmentation will push new boundaries in biomarker discovery and biopharmaceutical therapies
     
    To advance the detection and treatment of disease, it is critical to understand how thousands of proteins, lipids and metabolites in the body are regulated and modified. Biomarkers, the molecules that change when we are ill, are used by doctors as the “canary in the coal mine” warning system. So far, scientists have only scratched the surface in biomarker discovery. The ZenoTOF 7600 system will help scientists uncover more and better biomarkers, bringing us closer to true precision medicine where the right drug is given to the right patient at the right time.
     
    Compared to previous systems, the ZenoTOF 7600 system can quantify up to 40 percent more proteins and analyze samples five times faster for large biobank studies. In addition, EAD fragmentation brings new capabilities to understand how the proteins are post-translationally modified—an important but challenging area in biomarker research.
     
    “The ability to exactly tailor kinetic energy for EAD optimizes the MS/MS spectra and maximizes quantification accuracy. The use of Zeno trap pulsing provides significant gains in sensitivity, further improving the utility of this approach for characterizing PTMs,” said Birgit Schilling, Ph.D., associate professor, director of the Mass Spectrometry Center, The Buck Institute.
     
    The ZenoTOF 7600 system is transformational for lipidomics and can fully characterize an individual lipid from a single spectrum using EAD fragmentation. This will enable the discovery of novel lipid markers for cancer and inflammatory disease, precisely identifying and quantifying individual species that has been previously impossible.
     
    “We were never able to characterize all the way down to the double bond position of lipid species, or identify the exact position of side chains. I see the ZenoTOF 7600 system as a really important advancement in being able to completely profile the lipidome from the top to the bottom,” said James Cox, research associate professor at the University of Utah.
     
    To bring life-saving next-generation biopharmaceutical therapies to market quickly and safely, critical quality attributes must be rapidly and comprehensively analyzed. For the first time, EAD fragmentation allows biopharmaceutical scientists to precisely detect and quantify protein glycosylation patterns and differentiate isomeric amino acids. Both are critical to ensuring that therapies are safe and do not produce adverse reactions.
     
    “As biopharma scientists seek to develop more complex and sophisticated biotherapeutics, the challenge of analytics also becomes more complex. The ability of EAD to routinely and precisely characterize these biologics will change the game and make therapies accessible to patients much faster,” said Mani Krishnan, vice president and general manager, CE and Biopharma at SCIEX.
     
    SCIEX delivers solutions for the precision detection and quantification of molecules, empowering our customers to protect and advance the wellness and safety of all. The company has led the field of mass spectrometry for 50 years. From the launch of the first ever commercially successful triple quadrupole in 1981, SCIEX has developed groundbreaking technologies and solutions that influence life-changing research and outcomes. Today, as part of the Danaher family of global life science and technology innovators, SIEX continues to pioneer robust solutions in mass spectrometry and capillary electrophoresis. Its customers are able to quickly respond to environmental hazards, better understand biomarkers relevant to disease, improve patient care in the clinic, bring relevant drugs to market faster and keep food healthier and safer.
     
     
    Suggested For You
    Nissha Medical Technologies Nissha Medical Technologies
    Simbex Simbex
    WESTPAK Inc. WESTPAK Inc.
    BMP Medical - Delivering Custom Plastics Manufactured Solutions BMP Medical - Delivering Custom Plastics Manufactured Solutions
    High Tech Turning Co. Inc. High Tech Turning Co. Inc.
    Accu-Tube Appoints Matthew Haddle as CEO Accu-Tube Appoints Matthew Haddle as CEO
    Heraeus Acquires Mo-Sci Corporation, ETS Technology Holdings Heraeus Acquires Mo-Sci Corporation, ETS Technology Holdings
    MedTech Innovator Names the Finalists for the Title of MedTech Innovator 2021 MedTech Innovator Names the Finalists for the Title of MedTech Innovator 2021
    CareDx Appoints Hannah Valantine to its Board CareDx Appoints Hannah Valantine to its Board
    CE Mark Granted to Predictive Software for Kidney Allograft Survival CE Mark Granted to Predictive Software for Kidney Allograft Survival
    Babson Diagnostics Raises $31 Million in Series B Funding Babson Diagnostics Raises $31 Million in Series B Funding
    FDA Clears Inova Diagnostics FDA Clears Inova Diagnostics' Digital Multi-Analyte System
    PTI Engineered Plastics Wins a 2021 Macomb Business Award PTI Engineered Plastics Wins a 2021 Macomb Business Award
    Medical Devices Market to Top $671.49 Billion by 2027 Medical Devices Market to Top $671.49 Billion by 2027
    Minnesota Rubber and Plastics to Build New Innovation Center Minnesota Rubber and Plastics to Build New Innovation Center

    Related Buyers Guide Companies

    • Nissha Medical Technologies

      ...
      Amy Jeary, Market Development Manager 11.18.22

    • Simbex

      ...
      Greg Lange, Chief Business Development Officer 10.05.22

    • Packaging & Sterilization
      WESTPAK Inc.

      WESTPAK Inc.

      ...
      Tim Eells, WESTPAK, Inc. 03.04.22


    • BMP Medical - Delivering Custom Plastics Manufactured Solutions

      BMP Medical - Delivering Custom Plastics Manufactured Solutions

      Medical Contract Manufacturing, Design, Assembly & Packaging

    • High Tech Turning Co. Inc.

      ...
      Fred Sophis, Sales 11.02.21

    Loading, Please Wait..

    Trending
    • Cardiosense Begins SEISMIC-HF I Heart Failure Trial
    • Danaher Names New Environmental And Applied Solutions Company Veralto
    • Exo Introduces The Exo Iris To Market
    • A New Approach To Post-Market Surveillance
    • FDA Clears LiveMetric's Wearable Blood Pressure Monitoring Tech
    Breaking News
    • Former FDA Director Joins Greenleaf Health
    • Alexander D’Amico Named Chief Financial Officer at CytoSorbents
    • Moon Surgical Completes First U.S. Cases with Maestro System
    • Senseonics Finishes 365-Day CGM Study Cohort
    • Surface Solutions Group to Showcase GlideMed Coating at MD&M
    View Breaking News >
    CURRENT ISSUE

    September 2023

    • Superior Subtractive Solutions for Machining Medtech
    • Medical Device Industry Experts' Thought on Assembly & Automation
    • Power Trip: A Discussion of Custom Medical Electronics
    • The MDR Transition: An Opportunity for Design Change?
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    PLT Health Solutions Granted Claims for Botanical Ingredient in Canada
    CRN Files Petition with FTC For Clarity on Health Products Compliance Guidance
    Vitafoods Europe Relocates to Barcelona Starting 2025
    Coatings World

    Latest Breaking News From Coatings World

    AkzoNobel Names Sweet Embrace as Interpon Color of the Year 2024
    PPG’s New Paint for a New Start Transforms 27 Schools Worldwide with Colorful Makeovers
    PPG's New Paint for a New Start Initiative Transforms School for Children with Autism in Spain
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Alexander D’Amico Named Chief Financial Officer at CytoSorbents
    Moon Surgical Completes First U.S. Cases with Maestro System
    Senseonics Finishes 365-Day CGM Study Cohort
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Ginkgo Bioworks, Pfizer Enter Multi-Target RNA Discovery Alliance
    WuXi Vaccines Launches Vaccines CDMO Site in China
    MilliporeSigma Launches Integrated mRNA Services
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Top 10 Most Popular Fashion Designer Makeup Brands—According to Landys Chemist
    Jennifer Coolidge Collaborates with e.l.f. Cosmetics for 'Dirty Pillows' Lip Collection
    Victoria Beckham Beauty Introduces First Fragrance Collection
    Happi

    Latest Breaking News From Happi

    Wharton To Honor Leonard A. Lauder with Retail Excellence Award
    Extracts-Unlimited Attains Organic Certification
    Theraderm Clinical Skincare Launches Brilliance Boost Resurfacing Pads
    Ink World

    Latest Breaking News From Ink World

    Sapphire Ink – SB Eco Series Receives Oeko-Tex Eco Passport ZDHC Level 3 Certification
    Flint Group Digital with Xeikon Present at FEFCO Technical Seminar
    R.E. Carroll Inc. Packs, Donates 400 Backpacks to Students
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Bobst to 'unwrap the future of flexible packaging' at open house
    IDENTCO brings new automated wire marking system to Mexico
    Maan Engineering chooses Vetaphone for linerless labels
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Ana Fraisse Joins The American Cleaning Institute
    Weekly Recap: Soft N' Dry Seeks to Expand Private Label Roll Out, Albis Completes Work on Line
    Lenzing Earns EU Ecolabel at Indonesian Plant
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ONWARD Completes First-in-Human for ARC-IM to Restore Upper Extremity Function
    Michael S. Aronow Installed as AOFAS President
    Abyrx's MONTAGE Settable Bone Putty Cleared for Cardiothoracic Surgery
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    PPG and Flō-Optics Enter Exclusive Supplier Agreement
    SEMI North America Advisory Board Adds New Members
    Nhat Tin Logistics Enhances Operations with Zebra Technologies

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login