• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    FineHeart Successfully Tests Wireless TET System

    Apria Healthcare Settles Whistleblower Lawsuit

    OraSure’s OMNIgene·ORAL Device Included in COVID-19 EUA Amendment

    Remote Patient Monitoring Market Set to Surpass $645 Million by 2025

    4C Medical Technologies Completes $10 Million Over-Subscribed Convertible Note Financing
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Fixing Face Mask Form and Function

    The Heart of the Matter: Trends in Cardiology

    Virtually the Same? The Challenges of Online Conferences

    Digital Health Delivers During a Year for the Ages

    Advanced Technology for Staking and Swaging Medical Plastics
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    MW Life Sciences

    Spectrum Plastics Group

    Concise Engineering

    Qosina Corp.

    Unicep
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Meeting Critical Ventilator Product Requirements Amid Pandemic

    Impact of COVID-19 on the Medtech Supply Chain

    Finding the Upside to a Challenging Year

    Preparing Your Design Controls for FDA Approval

    A 'Trial and Error' Approach to Micromolded Parts
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Spectrum Plastics Group

    Qosina Corp.

    K-Tube Technologies

    PTI Engineered Plastics Inc.

    MW Life Sciences
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Brain Mapping Tool Generates High-Res Data During Surgery

    The new electrode grid is about a thousand times thinner than clinical electrode grids.

    Brain Mapping Tool Generates High-Res Data During Surgery
    The PEDOT:PSS electrode grid is a new brain mapping device that can be used during brain surgery. Image courtesy of David Baillot/UC San Diego Jacobs School of Engineering
    Related CONTENT
    • Thin-Film Electrodes for Brain Surgery Reach the Market
    • A Noninvasive Method for Deep Brain Stimulation
    • Making Brain Implants Smaller Could Prolong Their Lifespan
    • 3D Printing & Hollywood Special FX Help Train Neurosurgeons
    • NICO Announces CE Mark for BrainPath Non-Disruptive Cranial Access Technology
    UC San Diego Jacobs School of Engineering05.25.17
    Researchers have developed a new device to map the brain during surgery and distinguish between healthy and diseased tissues. The device provides higher resolution neural readings than existing tools used in the clinic and could enable doctors to perform safer, more precise brain surgeries.
     
    The device is an improved version of a clinical tool called an electrode grid, which is a plastic or silicone-based grid of electrodes that is placed directly on the surface of the brain during surgery to monitor the activity of large groups of neurons. Neurosurgeons use electrode grids to identify which areas of the brain are diseased in order to avoid damaging or removing healthy, functional tissue during operations. Despite their wide use, electrode grids have remained bulky and have not experienced any major advances over the last 20 years.
     
    The new electrode grid, developed by a team of researchers at the University of California San Diego and Massachusetts General Hospital, is about a thousand times thinner—6 micrometers versus several millimeters thick—than clinical electrode grids. This allows it to conform better to the intricately curved surface of the brain and obtain better readings. The new electrode grid also contains a much higher density of electrodes—spaced 25 times closer than those in clinical electrode grids—enabling it to generate higher resolution recordings.
     
    “Our goal is to develop a tool that can obtain more reliable information from the surface of the brain,” said electrical engineering professor Shadi Dayeh, who co-led the study with neuroscience professor Eric Halgren and electrical engineering professor Vikash Gilja, all at UC San Diego. The project was funded by the Center for Brain Activity Mapping (CBAM) at UC San Diego and brought together experts from multiple fields, including neurosurgeons, neuroscientists, electrical engineers, materials scientists and experts in systems integration. Researchers published their work on May 12 in Advanced Functional Materials.
     
    “By providing higher resolution views of the human brain, this technology can improve clinical practices and could lead to high performance brain machine interfaces,” Gilja said.
     
    To make their high-resolution electrode grid, researchers had to find a way to shrink the size of the electrodes to pack them closer together. But with metal electrodes, which are typically used to make these grids, there is a tradeoff—shrinking their size increases their electrical resistance, resulting in more noisy readings.
     
    To overcome this problem, the team switched out the metal electrodes with ones made of a conductive polymer called PEDOT:PSS. The material is transparent, thin and flexible. Using this material enabled researchers to make smaller electrodes without sacrificing electrochemical performance. It also enhanced the richness of the information measured from the surface of the brain.
     
    “These electrodes occupy minuscule volumes—imagine Saran wrap, but thinner. And we demonstrate that they can capture neural activity from the human brain at least as well as conventional electrodes that are orders of magnitude larger,” Gilja said.

    Researchers worked with neurosurgeons at Jacobs Medical Center at UC San Diego Health and Brigham Women’s Hospital in Boston to test their grid on four patients. The PEDOT:PSS electrode grid and a standard clinical electrode grid were compared side by side. In standard clinical recordings, the PEDOT:PSS electrode grid either performed similarly or slightly better than the standard electrode grid, recording with lower noise and higher resolution.
     
    “In order to introduce a new electrode grid for clinical use, we first need to show that the device can yield the same information as that used in the clinic. Then we can build upon that work to make an even better product that can improve patient care,” Dayeh said.
     
    In one test, the team performed background readings of a patient’s brain waves both while the patient was awake and unconscious. The PEDOT:PSS electrode grid produced similar readings as the standard clinical electrode grid. In another test, the team monitored the brain activity of a patient undergoing epilepsy surgery. Both electrode grids identified normal functioning areas of the brain versus where the seizures were happening. The main difference is that the PEDOT:PSS electrode grid produced more detailed and higher resolution readings than the clinical electrode grid.
     
    Other tests monitored the brain activity of patients performing cognitive tasks. Patients were either shown a particular word or a picture illustrating that word. The word was afterwards recited to the patients. In the readings from both the PEDOT:PSS and standard electrode grids, researchers could differentiate between when the patients were hearing the word versus when they were seeing it (or a picture). “This experiment shows we can resolve functional and cognitive activity from the surface of the brain using these electrodes,” Dayeh said.
     
    The team’s next steps are to make higher density electrode grids for improved resolution and biocompatibility tests to see how long they can stay in the body before they experience biofouling.
    Related Searches
    • led
    • tissue
    • human
    • san diego
    Related Knowledge Center
    • Neurological
    • Digital Health
    • Surgical
    Suggested For You
    Thin-Film Electrodes for Brain Surgery Reach the Market Thin-Film Electrodes for Brain Surgery Reach the Market
    A Noninvasive Method for Deep Brain Stimulation A Noninvasive Method for Deep Brain Stimulation
    Making Brain Implants Smaller Could Prolong Their Lifespan Making Brain Implants Smaller Could Prolong Their Lifespan
    3D Printing & Hollywood Special FX Help Train Neurosurgeons 3D Printing & Hollywood Special FX Help Train Neurosurgeons
     NICO Announces CE Mark for BrainPath Non-Disruptive Cranial Access Technology NICO Announces CE Mark for BrainPath Non-Disruptive Cranial Access Technology
    Personalized 3D Brain Maps to Guide Neurosurgeries Personalized 3D Brain Maps to Guide Neurosurgeries
    BrainPath Non-Disruptive Cranial Access Technology Wins CE Mark BrainPath Non-Disruptive Cranial Access Technology Wins CE Mark
    Surgeon Plans Procedure on Himself with 3D Visualization Surgeon Plans Procedure on Himself with 3D Visualization
    New Blood Test Could Locate Tumor Growing in the Body New Blood Test Could Locate Tumor Growing in the Body
    Carbon Electrode Transmitter Tracks Dopamine in the Brain Carbon Electrode Transmitter Tracks Dopamine in the Brain
    3D Printing the Human Vasculature 3D Printing the Human Vasculature
    First Commercial Procedures Performed Using Corindus Vascular Robotics First Commercial Procedures Performed Using Corindus Vascular Robotics' CorPath GRX System
    PathMaker Neurosystems, French Brain Institute Partner on Neuromodulation Device Trials PathMaker Neurosystems, French Brain Institute Partner on Neuromodulation Device Trials
    Microscopic Submarines for Your Stomach Microscopic Submarines for Your Stomach
    'Smart Needle' with Hair-Thin Camera Makes Brain Surgery Safer

    Related Breaking News

    • Neurological
      Cognito Therapeutics’ Lead Product Receives FDA Breakthrough Device Designation

      Cognito Therapeutics’ Lead Product Receives FDA Breakthrough Device Designation

      Next-generation digital therapeutic is designed for the treatment of Alzheimer’s disease.
      Business Wire 01.14.21

    • Surgical
      Moon Surgical Expands Leadership Team

      Moon Surgical Expands Leadership Team

      Adds Jeffery Alvarez, David Noonan, and Nicolas Linard.
      Moon Surgical 01.14.21

    • Neurological
      Medtronic Begins Adaptive Deep Brain Stimulation Trial for Parkinson

      Medtronic Begins Adaptive Deep Brain Stimulation Trial for Parkinson's

      First-of-its-kind study tests automated therapy that responds to brain signals in Parkinson's patients.
      PR Newswire 01.14.21


    • Patient Monitoring
      Valencell Launches Blood Pressure Monitoring Tech

      Valencell Launches Blood Pressure Monitoring Tech

      New technology can be built into a myriad of devices to provide accurate blood pressure readings.
      Valencell 01.13.21

    • Digital Health | Software & IT
      FDA Releases Artificial Intelligence, Machine Learning Action Plan

      FDA Releases Artificial Intelligence, Machine Learning Action Plan

      Outlines FDA’s next steps toward furthering oversight for AI/ML-based "software as a medical device."
      U.S. Food and Drug Administration 01.13.21

    • Chronic Disease | Digital Health | Patient Monitoring
      Teladoc Health, Dexcom Launch CGM Tech, Personalized Insights for Type 2 Diabetes

      Teladoc Health, Dexcom Launch CGM Tech, Personalized Insights for Type 2 Diabetes

      CGM-powered insights offer complete health profile, recommendations that support ongoing diabetes management.
      GlobeNewswire 01.13.21


    • Patient Monitoring
      Unique Contact Lens Sensor System & Manufacturing Process Developed

      Unique Contact Lens Sensor System & Manufacturing Process Developed

      New multifunctional lens can provide diversified signals from eyes.
      Surrey University 01.12.21

    • Neurological | Surgical
      FDA OKs ClearMind Biomedical

      FDA OKs ClearMind Biomedical's Axonpen Neuroendoscope

      Requires only a narrow channel of 6.5mm through the skull for insertion into the brain.
      PR Newswire 01.12.21

    • Patient Monitoring
      Itamar Medical Acquires Spry Health Tech, Assets

      Itamar Medical Acquires Spry Health Tech, Assets

      Leverages Spry’s technology to bring to market first device for continuous remote patient monitoring of sleep apnea.
      GlobeNewswire 01.12.21


    • Patient Monitoring
      CES News: Philips Highlights Healthcare at Home

      CES News: Philips Highlights Healthcare at Home

      Participates in the first-ever all-digital CES 2021.
      Royal Philips 01.11.21

    • Diagnostics | Neurological
      FDA OKs Abbott

      FDA OKs Abbott's First-of-Its-Kind Rapid, Handheld TBI Test

      Produces a result within 15 minutes after a plasma sample is inserted.
      Abbott Laboratories 01.11.21

    • Neurological
      BioSerenity Achieves FDA Clearance for Wearable Device System

      BioSerenity Achieves FDA Clearance for Wearable Device System

      Neuronaute EEG System and IceCap bring comprehensive remote electroencephalography monitoring services to people living with neurological disorders.
      PRNewswire 01.07.21


    • Packaging & Sterilization | Surgical
      Olympus Releases ScopeLocker Endoscope Storage Cabinet

      Olympus Releases ScopeLocker Endoscope Storage Cabinet

      HEPA hinged door endoscope storage system addresses infection prevention needs in busy GI suites.
      Olympus 01.06.21

    • Surgical
      FDA Clears EndoRotor to Remove Dead Pancreatic Tissue

      FDA Clears EndoRotor to Remove Dead Pancreatic Tissue

      Treats patients with necrotic tissue resulting from complications of acute pancreatitis.
      U.S. Food and Drug Administration 01.04.21

    • Cardiovascular | Neurological | Surgical
      FDA OKs Rapid Medical

      FDA OKs Rapid Medical's Steerable Neurovascular Guidewire

      Provides efficient access in difficult neuro and peripheral vascular procedures.
      Business Wire 01.04.21


    Trending
    • Cytotron Gains Breakthrough Status To Treat Breast, Liver, And Pancreatic Cancers
    • Portable, Home-Use Device Quickly Measures Inflammation Levels
    • 5 Ways Plastics Revolutionized The Healthcare Industry
    • Hardy Diagnostics Releases Rapid Test For COVID-19
    • Top 10 Trends In The Medical Device And Equipment Industry
    Breaking News
    • FineHeart Successfully Tests Wireless TET System
    • Apria Healthcare Settles Whistleblower Lawsuit
    • OraSure’s OMNIgene·ORAL Device Included in COVID-19 EUA Amendment
    • Remote Patient Monitoring Market Set to Surpass $645 Million by 2025
    • 4C Medical Technologies Completes $10 Million Over-Subscribed Convertible Note Financing
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Pharmaceutical Focus: A Look at Combination Products
    • The Printed World: Additive Manufacturing in Medtech
    • The Lost Year: 2020 Year in Review
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Qualitas Health/iwi Raises $10 Million in Investment Round
    Aker BioMarine Expands Krill Portfolio with Novel Protein Hydrolysate
    Cistanche Tubulosa Botanical Shown to Attenuate Locomotive Syndrome
    Coatings World

    Latest Breaking News From Coatings World

    Huntsman Finalizes Acquisition of Gabriel Performance Products
    PPG Completes COLORFUL COMMUNITIES Project at School in A. Bangsaothong Samutprakarn, Thailand
    dar-tech, inc. Becomes U.S. Midwestern Distributor for ZS Interpolymer
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    FineHeart Successfully Tests Wireless TET System
    Apria Healthcare Settles Whistleblower Lawsuit
    OraSure’s OMNIgene·ORAL Device Included in COVID-19 EUA Amendment
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Valeo Pharma Appoints President, COO
    Metrion, LifeArc Extend Neuroscience Alliance
    Grifols Begins COVID-19 Plasma Treatment Trial
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    JLo Beauty Launches at Sephora & Amazon
    Unilever and Alibaba Group Join Forces
    Redken Unveils Acidic Bonding Concentrate Range
    Happi

    Latest Breaking News From Happi

    A Surge in Interest for Supplements & Vitamins
    Manscaped Expands Further in Europe
    Color Street Gives Back
    Ink World

    Latest Breaking News From Ink World

    dar-tech, inc. Becomes U.S. Midwestern Distributor for ZS Interpolymer
    Techkon USA, Konica Minolta Partner
    Alon Bar-Shany Appointed Chairman of Highcon Board
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Exhibitor registration opens for virtual.drupa
    FTA planning in-person Forum & INFOFLEX
    Fortis Solutions Group achieves SGP certification
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Super Strong Inks Survive Tough Environments
    Ontex Honored for Mask Production
    TFP Acquires PV3 Technologies
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    OrthoPediatrics Expands Agent Network in Three European Countries
    Studies Show FlareHawk Expandable Cage Delivers Favorable Fusion, Patient Outcomes
    Rapid Recovery Protocol Can Lead to Increased Range of Motion After TKA
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    UDC Subsidiary Adesis' Website Wins 2020 MarCom Platinum Award
    Roadsimple Modernizes Warehouse Ops with Zebra Technologies
    Graphene Flagship Launches Redesigned Website

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login