• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    The Changing Face of Medtech Surface Treatment

    The Totally Tubular Technologies that Support Medical Devices

    Simply Stimulating: Examining the Neurostimulation Sector

    Sensing Technology Drives the Future of Medical Care

    New and Developing Diabetes Technologies Offer 'Sweet Relief'
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Regulatory
    Financial/Business
    Top News
    Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter

    Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs

    Bronwyn Brophy Named CEO at Vitrolife AB

    TRIMEDX Revamps its Management Team

    Illumina Releases Cloud-Based Software for Next-Gen Sequencing
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    The Changing Face of Medtech Surface Treatment

    The Totally Tubular Technologies that Support Medical Devices

    Simply Stimulating: Examining the Neurostimulation Sector

    Sensing Technology Drives the Future of Medical Care

    New and Developing Diabetes Technologies Offer 'Sweet Relief'
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Timeline Mystery for Updated EtO Rules

    An Update on Hospital Trends Post-Pandemic

    Don’t Fear the Audit: Benefits of Good Quality Practices

    Understanding the FDA’s Standards & Conformity Assessment Program

    Medtech Divestitures Are Good for Medtech Innovation
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    JBC Technologies

    LEMO USA Inc.

    Fusion Biotec Inc.

    Medbio LLC

    Arthur G. Russell Co. Inc., The
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Designing for Manufacturing: 5 Common Startup Mistakes (and How to Avoid Them)

    5 Challenges Medtech Must Address to Transform Health Care

    3D Printing Medical Devices Revolutionized Manufacturing

    5 Current Trends in Medical Device Security

    How Advanced Sensors Improve Design & Functionality of Respiratory Care Equipment
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    JBC Technologies

    LEMO USA Inc.

    Fusion Biotec Inc.

    Medbio LLC

    Arthur G. Russell Co. Inc., The
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • eBook
    • Resources
    • Podcasts
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Brain Mapping Tool Generates High-Res Data During Surgery

    The new electrode grid is about a thousand times thinner than clinical electrode grids.

    Brain Mapping Tool Generates High-Res Data During Surgery
    The PEDOT:PSS electrode grid is a new brain mapping device that can be used during brain surgery. Image courtesy of David Baillot/UC San Diego Jacobs School of Engineering
    UC San Diego Jacobs School of Engineering05.25.17
    Researchers have developed a new device to map the brain during surgery and distinguish between healthy and diseased tissues. The device provides higher resolution neural readings than existing tools used in the clinic and could enable doctors to perform safer, more precise brain surgeries.
     
    The device is an improved version of a clinical tool called an electrode grid, which is a plastic or silicone-based grid of electrodes that is placed directly on the surface of the brain during surgery to monitor the activity of large groups of neurons. Neurosurgeons use electrode grids to identify which areas of the brain are diseased in order to avoid damaging or removing healthy, functional tissue during operations. Despite their wide use, electrode grids have remained bulky and have not experienced any major advances over the last 20 years.
     
    The new electrode grid, developed by a team of researchers at the University of California San Diego and Massachusetts General Hospital, is about a thousand times thinner—6 micrometers versus several millimeters thick—than clinical electrode grids. This allows it to conform better to the intricately curved surface of the brain and obtain better readings. The new electrode grid also contains a much higher density of electrodes—spaced 25 times closer than those in clinical electrode grids—enabling it to generate higher resolution recordings.
     
    “Our goal is to develop a tool that can obtain more reliable information from the surface of the brain,” said electrical engineering professor Shadi Dayeh, who co-led the study with neuroscience professor Eric Halgren and electrical engineering professor Vikash Gilja, all at UC San Diego. The project was funded by the Center for Brain Activity Mapping (CBAM) at UC San Diego and brought together experts from multiple fields, including neurosurgeons, neuroscientists, electrical engineers, materials scientists and experts in systems integration. Researchers published their work on May 12 in Advanced Functional Materials.
     
    “By providing higher resolution views of the human brain, this technology can improve clinical practices and could lead to high performance brain machine interfaces,” Gilja said.
     
    To make their high-resolution electrode grid, researchers had to find a way to shrink the size of the electrodes to pack them closer together. But with metal electrodes, which are typically used to make these grids, there is a tradeoff—shrinking their size increases their electrical resistance, resulting in more noisy readings.
     
    To overcome this problem, the team switched out the metal electrodes with ones made of a conductive polymer called PEDOT:PSS. The material is transparent, thin and flexible. Using this material enabled researchers to make smaller electrodes without sacrificing electrochemical performance. It also enhanced the richness of the information measured from the surface of the brain.
     
    “These electrodes occupy minuscule volumes—imagine Saran wrap, but thinner. And we demonstrate that they can capture neural activity from the human brain at least as well as conventional electrodes that are orders of magnitude larger,” Gilja said.

    Researchers worked with neurosurgeons at Jacobs Medical Center at UC San Diego Health and Brigham Women’s Hospital in Boston to test their grid on four patients. The PEDOT:PSS electrode grid and a standard clinical electrode grid were compared side by side. In standard clinical recordings, the PEDOT:PSS electrode grid either performed similarly or slightly better than the standard electrode grid, recording with lower noise and higher resolution.
     
    “In order to introduce a new electrode grid for clinical use, we first need to show that the device can yield the same information as that used in the clinic. Then we can build upon that work to make an even better product that can improve patient care,” Dayeh said.
     
    In one test, the team performed background readings of a patient’s brain waves both while the patient was awake and unconscious. The PEDOT:PSS electrode grid produced similar readings as the standard clinical electrode grid. In another test, the team monitored the brain activity of a patient undergoing epilepsy surgery. Both electrode grids identified normal functioning areas of the brain versus where the seizures were happening. The main difference is that the PEDOT:PSS electrode grid produced more detailed and higher resolution readings than the clinical electrode grid.
     
    Other tests monitored the brain activity of patients performing cognitive tasks. Patients were either shown a particular word or a picture illustrating that word. The word was afterwards recited to the patients. In the readings from both the PEDOT:PSS and standard electrode grids, researchers could differentiate between when the patients were hearing the word versus when they were seeing it (or a picture). “This experiment shows we can resolve functional and cognitive activity from the surface of the brain using these electrodes,” Dayeh said.
     
    The team’s next steps are to make higher density electrode grids for improved resolution and biocompatibility tests to see how long they can stay in the body before they experience biofouling.
    Related Searches
    • medical
    • it
    • body
    • silicone
    Related Knowledge Center
    • Digital Health
    • Surgical
    • Patient Monitoring
    • Neurological
    Suggested For You
    Longeviti Launches ClearFit Covers for Brain Surgery Patients Longeviti Launches ClearFit Covers for Brain Surgery Patients
    Encora Encora's Tremor Reducing Wristband Gains Breakthrough Status
    Thin-Film Electrodes for Brain Surgery Reach the Market Thin-Film Electrodes for Brain Surgery Reach the Market
    A Noninvasive Method for Deep Brain Stimulation A Noninvasive Method for Deep Brain Stimulation
    Making Brain Implants Smaller Could Prolong Their Lifespan Making Brain Implants Smaller Could Prolong Their Lifespan
    3D Printing & Hollywood Special FX Help Train Neurosurgeons 3D Printing & Hollywood Special FX Help Train Neurosurgeons
     NICO Announces CE Mark for BrainPath Non-Disruptive Cranial Access Technology NICO Announces CE Mark for BrainPath Non-Disruptive Cranial Access Technology
    Personalized 3D Brain Maps to Guide Neurosurgeries Personalized 3D Brain Maps to Guide Neurosurgeries
    BrainPath Non-Disruptive Cranial Access Technology Wins CE Mark BrainPath Non-Disruptive Cranial Access Technology Wins CE Mark
    Surgeon Plans Procedure on Himself with 3D Visualization Surgeon Plans Procedure on Himself with 3D Visualization
    New Blood Test Could Locate Tumor Growing in the Body New Blood Test Could Locate Tumor Growing in the Body
    Carbon Electrode Transmitter Tracks Dopamine in the Brain Carbon Electrode Transmitter Tracks Dopamine in the Brain
    3D Printing the Human Vasculature 3D Printing the Human Vasculature
    First Commercial Procedures Performed Using Corindus Vascular Robotics First Commercial Procedures Performed Using Corindus Vascular Robotics' CorPath GRX System
    PathMaker Neurosystems, French Brain Institute Partner on Neuromodulation Device Trials PathMaker Neurosystems, French Brain Institute Partner on Neuromodulation Device Trials

    Related Breaking News

    • Longeviti Launches ClearFit Covers for Brain Surgery Patients

      Longeviti Launches ClearFit Covers for Brain Surgery Patients

      ClearFit Implants can reconstruct the skull and be used as a diagnostic tool.
      Michael Barbella, Managing Editor 04.01.21

    • Neurological
      Encora

      Encora's Tremor Reducing Wristband Gains Breakthrough Status

      Indicated to provide temporary hand tremor relief in adult essential tremor or Parkinson's patients.
      Sam Brusco, Associate Editor 03.31.21

    • Electronics | Neurological
      Thin-Film Electrodes for Brain Surgery Reach the Market

      Thin-Film Electrodes for Brain Surgery Reach the Market

      An important advancement for treating patients with epilepsy and brain tumors.
      Dave Rosa, President and CEO, NeuroOne Medical Technologies Corporation 06.30.20


    • Neurological
      A Noninvasive Method for Deep Brain Stimulation

      A Noninvasive Method for Deep Brain Stimulation

      Electrodes placed on the scalp could help patients with brain diseases.
      Anne Trafton, MIT News Office 06.02.17

    • Neurological
      Making Brain Implants Smaller Could Prolong Their Lifespan

      Making Brain Implants Smaller Could Prolong Their Lifespan

      Thin fibers could be used to deliver drugs or electrical stimulation, with less damage to the brain.
      Anne Trafton, MIT News Office 05.16.17

    Loading, Please Wait..

    Trending
    • Masimo Reveals Freedom Health-Tracking Smartwatch
    • FDA OKs FemDx Medsystems' FalloView Device
    • Getinge’s Cardiosave Faces CE-Certificate Suspension From TÜV SÜD
    • Designing For Manufacturing: 5 Common Startup Mistakes (and How To Avoid Them)
    • Illumina Releases Cloud-Based Software For Next-Gen Sequencing
    Breaking News
    • Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter
    • Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs
    • Bronwyn Brophy Named CEO at Vitrolife AB
    • TRIMEDX Revamps its Management Team
    • Illumina Releases Cloud-Based Software for Next-Gen Sequencing
    View Breaking News >
    CURRENT ISSUE

    March 2023

    • Sensing Technology Drives the Future of Medical Care
    • New and Developing Diabetes Technologies Offer 'Sweet Relief'
    • Discussing Matters of Substance in Medtech Materials
    • Medical Device Testers Are Caught Up in a Whirlwind
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Wiley Eliminates Outer Carton From Packaging to Reduce Waste
    ACG Expands as Vantage Nutrition Acquires ComboCap and its Dual-Chamber Capsule Technology
    Melodea Launches New Plastic-Free Packaging Solution
    Coatings World

    Latest Breaking News From Coatings World

    AkzoNobel Appoints Ricardo Rosso as Pontiac Site Manager
    Sherwin-Williams Publishes Sustainable Packaging White Paper
    Heubach Launches Automotive Styling Shades 2027
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter
    Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs
    Bronwyn Brophy Named CEO at Vitrolife AB
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Evotec, BMS Expand Strategic Neurodegeneration Pact
    Regeneron, Sonoma Biotherapeutics Partner on Treg Cell Therapies
    Astellas, MIMETAS Enter Strategic Immuno-Oncology Alliance
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Millie Bobby Brown’s Florence by Mills Launches Eye-Centric Color Cosmetics Line
    Colorsmith Introduces ‘Salon-Quality’ Stylers for Men
    Panama Jack Launches Tropical Fragrances, Essential Oils & Body Mists
    Happi

    Latest Breaking News From Happi

    Kao Launches Space Shampoo Sheet
    Procter & Gamble Brings Tide ‘Loads of Hope’ Relief to Residents Affected by Deadly Tornado Outbreak in Mississippi
    Sederma Introduces Active Ingredient to Address Pigment Disorders
    Ink World

    Latest Breaking News From Ink World

    NAPIM Honors 2023 Ault, Pioneer Award Recipients
    Kodak to Showcase Prepress and Print Technologies at Print China 2023
    CPIPC Hosts Technical Dinner
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    CORLABEL invests in HP and a second GM finishing machine
    Elkem's Sean Duffy receives AWA Leadership Award
    eProductivity Software acquires Tharstern Group
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Ahlstrom Releases Sustainability Report
    Albaad Uses Upgrades Lenzing Fibers in Flushable Wipes
    Midwest Filtration, Monadnock Announce Partnership in Filtration
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Conventus Flower Ortho Appoints Jeff Culhane as COO
    Solid Growth Forecast for OTC Braces and Supports Market
    Exactech Boosts AI Expertise with Licensing Deal, Team of Scientists
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Japan Display to Acquire JOLED IP
    Graphenest, Hubron to Partner on Graphene Project
    CSEM Nominates Andreas Rickenbacher as New Chair of the Board

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login