• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    Butterfly Network Appoints New Leader

    BD Names Chairman of Board

    Interplex Acquires OCP Group

    FDA Clears a Portable Hemodialysis System

    Solid Growth Forecast for India's HER2 Amplification Tests Market
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Fixing Face Mask Form and Function

    The Heart of the Matter: Trends in Cardiology

    Virtually the Same? The Challenges of Online Conferences

    Digital Health Delivers During a Year for the Ages

    Advanced Technology for Staking and Swaging Medical Plastics
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    maxon

    PTI Engineered Plastics Inc.

    Concise Engineering

    Unicep

    Qosina Corp.
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Meeting Critical Ventilator Product Requirements Amid Pandemic

    Impact of COVID-19 on the Medtech Supply Chain

    Finding the Upside to a Challenging Year

    Preparing Your Design Controls for FDA Approval

    A 'Trial and Error' Approach to Micromolded Parts
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    PTI Engineered Plastics Inc.

    Spectrum Plastics Group

    maxon

    K-Tube Technologies

    Medicoil
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Features

    Four Considerations for Developers of Next-Generation Combination Products

    Bringing together real-time monitoring, telemedicine, AI, interventions, and pharmaceuticals into a single device produces a number of potential pitfalls.

    Four Considerations for Developers of Next-Generation Combination Products
    Features of the BoltMed combination drug-device product.
    Mark Goodman and Barry Thompson, Baker & McKenzie LLP03.04.20
    Jerry Smith is a 65-year-old male with a personal and family history of atherosclerotic cardiovascular disease (ASCVD), a medical condition that has caused more morbidity and mortality over the past half century than any other disease on the planet. Jerry’s father died at age 63 of a heart attack from ASCVD. Now, two years beyond his father’s age at the time of his death, Jerry feels the onset of pain in his chest radiating down his arm. His father described the same symptoms just before he had his fatal heart attack. Seemingly, Jerry’s genetics and less-than-healthy-lifestyle have combined to send him to the same early grave as his father. But, Jerry has two advantages over his father: Jerry knows what happened to his father and Jerry made a plan.

    Six months ago, Jerry’s cardiologist recommended a new product designed to save people at serious risk of ASCVD from events like heart attacks and strokes. The new product monitors for signs and symptoms of major ASCVD events and is capable of treating these events on an emergency basis. Three months ago, Jerry was implanted with the device (called BoltMed), a cutting-edge combination medical product approved as both a medical device and a pharmaceutical product. A cardiologist’s dream, this device has real-time monitoring capability (heart rate and heart rhythm), includes artificial intelligence (AI) technology that captures and analyzes Jerry’s personal data, and communicates with Jerry, his cardiologist, and emergency medical services. Even more amazingly, in emergency situations, the device can make medical decisions (just like Jerry’s physician) to deliver a defibrillating shock, dose Jerry with medication that treats cardiovascular events, or both.

    In this fictional scenario, the BoltMed device detects a cardiac event through monitoring Jerry’s data, administers appropriate treatment to Jerry (shock and/or medication), and alerts emergency services (EMS) and his physician. Jerry is rushed to the hospital, and he suffers no permanent damage to his heart and lives happily to the age of 80.

    How far is this from a real-world scenario? The answer is not very far. From our vantage, practicing in a global law firm that works day-in-and-day-out with small, medium, and large pharmaceutical, medical device, and biotech companies, these types of integrated products are already here in varying stages of development. Everyone in the medical field realizes future products will bring together real-time monitoring, data, connectivity at multiple levels, telemedicine and AI features, and treatment decisions that will, in certain circumstances, be made without physician intervention. But when complex products that take on so many functions are combined—often as part of collaboration and a co-promotion deal—there are a vast number of legal and regulatory considerations to be addressed.

    To help companies and interested parties through this process, this article will illustrate several of the aforementioned considerations and make suggestions on how to get these products to market and, once that is accomplished, how to manage and commercialize the product so it will thrive in today’s challenging legal and regulatory climate.

    1. Complex and Challenging Regulatory Scheme
    The top three markets for drug and device sales worldwide are the United States, Germany, and Japan, with the U.S. responsible for over 50 percent of all revenues in the industry. So, as companies think about developing and commercializing integrated combination drug and device products, these markets should obviously be the main focus.

    From a regulatory approval/market authorization standpoint, combination products like BoltMed are treated as two or possibly even three entirely separate products because they include an implanted medical device (with monitoring and defibrillation capability), complex software (with an algorithm that “thinks” and “acts”), and a drug delivered through a catheter port. Given this reality, the product sponsor may need to submit an application to more than one arm of the relevant regulatory body. In Japan, the combination product would be submitted to the Ministry of Health, Labor and Welfare (MHLW), and a determination made on a case-by-case basis whether the product will be marketed as a single drug, medical device, or regenerative medicine product. The product would not need to be submitted to MHLW as both a drug and a device. By contrast, in Europe, the European Medicines Agency (EMA) would require the proposed market authorization holder to submit the product to both its drug and device divisions, and the AI software would likely be submitted to both divisions as well.

    Certainly, the software component of any device that monitors and makes diagnostic and treatment decisions will undergo heavy scrutiny if it has AI and telemedicine features. In the U.S., the Food & Drug Administration (FDA) has an office dedicated to evaluate combination products, so all such products (including those with sophisticated software) should start there for evaluation. The more complex and multi-functional the software—especially when it has monitoring, diagnostic, and interventional components, and is effectively making diagnostic and treatment decisions ahead of the patient’s treating physician—will require significant clinical evaluation. It is highly likely such a product will be approved only with a risk evaluation and mitigation strategy (REMS) for post-market assessment of safety and labeling. Among other things, AI software will need to learn the difference between a normal versus an abnormal patient presentation using some type of approved protocol for undertaking that assessment, as well as a protocol for detecting and treating a significant abnormality. These requirements pose major clinical development challenges in terms of proving safety and efficacy and a favorable risk-benefit profile of the protocols and the functionality of the software.

    A reasonable strategy for gaining approval/market authorization is to break the analysis into its component parts and seek to take advantage of predicate devices, including those that have proven risk-benefit profiles. Using BoltMed as an example, defibrillators, defibrillator leads, electrocardiogram sensors, and catheters for drug delivery all have proven track records of safety and efficacy. The main challenges in proving the safety and efficacy of a new, integrated device like BoltMed will likely be around those components or drugs that are less-well-studied and/or have no predicate. In the context of our fictional case study, that would likely be the sensing mechanism, algorithm (for diagnosis, defibrillation, and drug delivery), and new branded medication (to be dispensed via the catheter port).

    To reiterate, the AI aspect of any product will be subjected to heavy scrutiny and require a large amount of clinical data to prove safety and efficacy. Though the medical community agrees the use and application of AI in drug and device development and medical care is the future of the healthcare industry, AI remains a new and largely untested concept. Certainly, AI is being used or at least contemplated in many products in development before FDA, EMA, and other regulatory agencies, and those agencies are gaining increasing knowledge and experience with such products that should eventually transfer to drug and device developers and help speed their products to market. But, the bottom line is that AI is still in its early stages and presents significant risk in the eyes of the regulators so any product that seeks to incorporate it in any respect will be carefully reviewed.

    2. Data Privacy and Cybersecurity
    The BoltMed medical product can be paired with wearable technology that collects and monitors patient data, and the device has AI, telemedicine, and EMS-contacting features. These are all good elements, so why are we worried about data privacy issues?

    The answer is we know any product that collects, stores, and transmits personal health data must comply with the latest data privacy regimes across the world, including (but not limited to) the Health Insurance Portability and Accountability Act (HIPAA), the California Medical Information Act (CMIA), the California Consumer Privacy Act (CCPA), and General Data Protection Regulation (GDPR). These privacy regimes are challenging because they are not uniform and continue to be updated and augmented on a virtually never-ending basis. The scope and complexity of worldwide data privacy laws would require a treatise all on its own. As such, the only advice offered here to any company with a product that touches personal data (especially health data): consult a qualified attorney regarding a data protection plan, comply with applicable rules and regulations, and prepare in the event something goes wrong. Simply put, data privacy regimes are here to stay and they cannot (and should not) be ignored. Nor should anyone ignore the very real risk of cybersecurity and data breach where their devices collect, store, and transmit personal data.

    We all understand the need for cybersecurity in our work and personal lives, and with connected, multi-functional combination products, the need is even greater. Here is the reality: Any company that is developing and selling a connected product needs to make cybersecurity a major focus of its business. Such companies need to spend the money to develop a robust defense against hacking and need to be realistic that, even if they do so, they will eventually get hacked. Companies need a plan for dealing with the inevitable because, even using the best and most up-to-date software, it is only a matter of time before an intrusion or breach happens; even the NSA has been hacked and it obviously has world-class programmers and security. Thus, firewalls, alarms, and anti-hacking systems should be put in place to fend off attacks and the company should have a plan in place to deal with attempted intrusions to demonstrate best practices. Mock attacks should be run and practiced once a month or once every two months, and everyone in the company must know how to react and what his/her role is in the event of an attack or breach. The company also needs to be able to investigate attempts/intrusions in real-time and, to the extent it concludes a breach has occurred, have a state-of-the-art response plan in place and follow that plan to inform consumers and regulators.

    The risk to patients (and companies) is all the more real when a product is a potential life-saving integrated combination device. What if hackers find their way into the product or a server and change the settings or disarm the device? Patients could be medically compromised or otherwise left unprotected. If this should happen, a company may find itself before a U.S. jury having to explain what it did (or did not do) to prevent hacking and/or how it set up its systems to protect patients from harm. That company better have a good story to tell and it should include, at the very least, “We put patient safety first and we planned for and tried our best to stop this from happening.” The only way to be able to say those things is to ensure the appropriate protective systems and plans are in place and operative, well in advance of any attack, and to try to stay up-to-date from a technological and readiness standpoint.

    3. My Product Actually Made It to Market—Now What?
    Company X made it to the market after spending hundreds of millions of dollars in development. It has an approved indication for a combination product and an approved label and/or instructions for use. Now what? Company X has to get out there and start talking to physicians about the product. But how does it do that? Company X must recruit and train an ethical sales force that will have direct contact with healthcare providers and promote its product for the approved indications, using approved messaging [materials approved by its compliance team and the respective regulator(s)], and detail the product while maintaining a fair balance in terms of describing the risks and benefits of the product. These things sound simple but, in the real world, when face-to-face with physicians, they are often difficult to get right.

    For example, if a sales representative is in the operating room helping identify medical instruments for a surgeon and the surgeon asks the sales representative how another surgeon uses the product to perform an unapproved or off-label procedure, what should the representative say? This, of course, happens all the time; it is a very awkward position for the sales representative to find oneself in, and it has potentially serious consequences for the company. Almost half of the major civil litigations and government enforcement actions brought over the past 20 years have had to do with off-label promotion claims and those claims have resulted in the recovery of billions of dollars in settlements, judgments, and penalties against healthcare companies.

    Other scenarios that vex sales representatives are, for example, where a physician asks the sales representative to bring expensive lunches in for his/her staff on a weekly basis or asks the representative to obtain an expensive “gift,” like concert tickets. What can and should the sales representative do under these circumstances? The answer is to comply with federal law and company policies and procedures for proper interactions with healthcare providers. But, for these people on the front lines (engaging day-in-and-day-out with physicians), there are countless scenarios everyday where they must make judgment calls on the fly as to what falls within the regulatory requirements for interactions with physicians and their own company’s accepted practices. It is a tough situation because they absolutely have to get it right, while under pressure from a physician with whom they are trying to establish a meaningful connection. And, the reason they have to get it right is because their conduct and interactions with physicians is under scrutiny and has serious repercussions for the company. As previously noted, this conduct and these interactions are frequently the basis for regulatory enforcement actions by FDA, EMA, or others. They can form the basis of civil or criminal actions based on the federal False Claims Act or lawsuits based on off-label promotion or other improper advertising/promotion. The consequences can be more than just substantial money damages and penalties: Such conduct can result in suspension or the loss of approval/market authorization to sell the drug/device and criminal penalties. Training and proctoring sales representatives is absolutely mission critical. These personnel will drive sales but they can also drive you out of business. Sales representatives need to be more than just an attractive face or personality. They need to be the driving force helping get across the profile and indications for the company’s product while accurately conveying the risk and benefit information for the product.

    In short, a company needs to make clear patient safety is its top priority, followed closely by the goal of accurately and fairly conveying the risk and benefit profile of its product. Not only is this the right thing to do from an ethical standpoint, regulators and the plaintiffs’ bar will be watching products and conduct to ensure companies are about safety first.

    4. The Pharmacovigilance System
    Because most products come onto the market with clinical evidence from only a few thousand patients, new and important safety and labeling data often emerge once the product is on the market and in wider use. As previously noted, complex, integrated products like BoltMed would almost certainly be approved with some type of REMS program for postmarket monitoring. The company would be expected to collect and analyze the product’s safety data and report trends or concerns to FDA and/or EMA, as required by the REMS. Of course, even for products approved without a REMS, a pharmacovigilance system must be in place that tracks expected and unexpected adverse events and identifies new events or patterns of events not previously recognized. Signal detection tools are available and highly recommended to assist with this pharmacovigilance process. All potential signals should be reviewed and assessed, and a careful record made as to how and why the company reacted as it did to the potential signal.

    Based on many decades of experience in litigation over emerging adverse events, companies should be more willing to proactively address data showing adverse events and to add such events to their labels/disclosures. Most of the largest pharmaceutical or medical device products liability litigations filed over the past two decades have resulted from newly discovered adverse events that never made it to the product labeling. The legal theory is the company failed to warn of the new risk and thus, the patient in consult with the physician was not able to make an informed decision about using the drug or device. But, it goes without saying there is no failure to warn when a company adds the event to its labeling. Although the major battle in such a civil litigation is almost always over how the label lists the risk at issue, based on taking the depositions of thousands of treating physicians and their patients, very few actually read the product’s label. In other words, though drug and device companies may fret over adding an event to the label, it is rare to hear of a regulator or physician that disapproved of this approach, and there is probably little risk that adding a new event to the label will change the physician’s prescribing behavior or a consumer’s purchasing decision. On the other hand, the failure to do so could lead to substantial civil liability, receipt of a warning letter, and/or significant brand damage.

    Conclusion
    The emphasis in this context should be on making good products and delivering them safely to physicians and consumers with full transparency. If the focus remains on these issues, and assuming the product works well and has significant utility, the commercial piece will fall into place and the legal and regulatory risks will be well-contained.

    [Author’s Note: The authors thank and acknowledge contributions to this article by their Baker McKenzie colleagues Els Janssen (Brussels), Takumi Hasegawa (Tokyo), and Khelin Aitken (Washington D.C.).]


    Mark Goodman is a partner at Baker & McKenzie LLP. Based in San Francisco, he serves as co-chair of the firm’s North America Commercial Litigation group and is part of the North America Trial Team. Goodman has led complex multi-district litigation, handled class actions, and tried cases in state and federal courts across the U.S. for both domestic and international healthcare and life sciences clients. He regularly presents on product liability, risk mitigation, and cross-border disputes.

    Barry Thompson is also a partner at Baker & McKenzie. Based in Los Angeles, he has litigated and tried complex commercial and product liability cases in state and federal courts across the country. Thompson has deep experience in cases with complex medical and scientific issues. As such, his practice focus has been on products liability, commercial, as well as litigation and risk management counseling. He is a member of the Firm’s National Trial Team and the Litigation Chair for Baker’s California Offices. 
    Related Searches
    • Software
    • defibrillator
    • labeling
    • cybersecurity
    Related Knowledge Center
    • R&D & Design

    Related Features

    • R&D & Design
      The Human Factors of Aesthetics

      The Human Factors of Aesthetics

      Exploring the relationship between a device’s aesthetic, human factors engineering, and purposeful design.
      Sean Hägen, Principal, Director of Research & Synthesis, BlackHägen Design 09.01.20

    • R&D & Design
      Current State of (Design) Mind

      Current State of (Design) Mind

      Medtech designers have an array of new tools to use for medical device development, enabling better solutions for healthcare.
      Mark Crawford, Contributing Writer 05.01.20

    • R&D & Design
      Examining the Usability of Medical Software

      Examining the Usability of Medical Software

      Developers need to consider the ‘human factor’ when it comes to testing medical device software.
      Bruce Johnston, Senior Software Engineering Specialist, MedAcuity Software 04.01.20


    • R&D & Design
      Inventive Interaction: Medtech Research and Development in 2020

      Inventive Interaction: Medtech Research and Development in 2020

      Engaging with all stakeholders—patients, clinicians, and community members alike—is key to effective medtech R&D.
      Michael Barbella, Managing Editor 01.29.20

    • Contract Manufacturing | Materials | R&D & Design
      Delivering the Goods: The Evolving World of Combination Products

      Delivering the Goods: The Evolving World of Combination Products

      This extremely diverse market fosters relationships between medical device and pharmaceutical companies.
      Sam Brusco, Associate Editor 11.04.19

    • Cardiovascular | Contract Manufacturing | Diagnostics | Digital Health | Electronics | Neurological | Patient Monitoring | R&D & Design
      Customized Connections: A Discussion on Custom Electronics

      Customized Connections: A Discussion on Custom Electronics

      Demand for more complex, traceable, integrated solutions are driving innovation in the fast-changing medical electronics market.
      Michael Barbella, Managing Editor 09.09.19


    • R&D & Design
      Consumer-Minded Design

      Consumer-Minded Design

      OEMs are requiring design partners to put more focus on user interface and aesthetics as they seek to produce devices intended to be used directly by patients.
      Mark Crawford , Contributing Writer 05.01.19

    • R&D & Design | Software & IT | Testing
      Transformative Testing: Addressing Patient Safety and Cybersecurity

      Transformative Testing: Addressing Patient Safety and Cybersecurity

      With changing regulatory landscapes and requirements, testing providers are being asked to do more in terms of ensuring the safety of medical devices.
      Mark Crawford, Contributing Writer 03.07.19

    • Materials | R&D & Design
      Sum and Substance: Material Considerations for Changing Design Needs

      Sum and Substance: Material Considerations for Changing Design Needs

      Material science and medical device development have a symbiotic relationship; advancement in one encourages innovation in the other.
      Sam Brusco, Associate Editor 03.07.19


    • R&D & Design
      Valued R&D: The Transformation of Medical Device Research and Development

      Valued R&D: The Transformation of Medical Device Research and Development

      Rising healthcare costs, limited reimbursements, and the pace of technological change is forcing medtech companies to find creative R&D solutions.
      Michael Barbella, Managing Editor 01.30.19

    • Contract Manufacturing | Machining & Laser Processing | Molding | Packaging & Sterilization | R&D & Design | Testing | Tubing & Extrusion
      Addressing Peak Issues in Medtech

      Addressing Peak Issues in Medtech

      The 2018 MPO Summit heads to Colorado for discussion, education, and networking.
      Sean Fenske, Editor-in-Chief 07.26.18

    • R&D & Design
      The DNA of Emotional Design

      The DNA of Emotional Design

      Designing user experiences to optimize the clinical team’s performance.
      Bryce G Rutter, Ph.D., Founder & CEO, Metaphase Design Group Inc. 07.26.18


    • R&D & Design
      Designing from Finish to Start

      Designing from Finish to Start

      When developing products for a value-based environment, it can be helpful to consider the end result first.
      Steve Maylish and Vicki Caiati 05.03.18

    • R&D & Design
      R&D Reboot: Leveraging New Strategies for Innovation Creation

      R&D Reboot: Leveraging New Strategies for Innovation Creation

      Medtech companies must adopt new research and development models to remain relevant and competitive in an evolving healthcare
      Michael Barbella, Managing Editor 01.29.18

    • Contract Manufacturing | R&D & Design
      An Outsourcing Focus in San Diego

      An Outsourcing Focus in San Diego

      The MPO Summit travels to southern California for sun, surf, networking, and industry insights.
      Sean Fenske, Editor 07.26.17


    Trending
    • Senseonics Forges Strategic Collaboration With Ascensia Diabetes Care
    • Portable, Home-Use Device Quickly Measures Inflammation Levels
    • Top 10 Trends In The Medical Device And Equipment Industry
    • Masimo Earns CE Mark For New Fingertip Pulse Oximeter
    • At-Home COVID-19 Test Kits Boosts Disease Monitoring Capabilities
    Breaking News
    • Butterfly Network Appoints New Leader
    • BD Names Chairman of Board
    • Interplex Acquires OCP Group
    • FDA Clears a Portable Hemodialysis System
    • Solid Growth Forecast for India's HER2 Amplification Tests Market
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Pharmaceutical Focus: A Look at Combination Products
    • The Printed World: Additive Manufacturing in Medtech
    • The Lost Year: 2020 Year in Review
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Omega-3s Evidenced to Reduce Low-Grade Inflammation in Elderly Men
    MIND and Mediterranean Diets Linked to Later Onset of Parkinson’s Disease
    Kerry Launches Web-Based Tool for Plant-Based Formulation Challenges
    Coatings World

    Latest Breaking News From Coatings World

    Keyland Polymer UV Powder, LLC Launches UVMax Defender
    Scott McLaughlin to Race in PPG Colors During Rookie INDYCAR Season
    Vink Chemicals Offers parmetol PSG
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Butterfly Network Appoints New Leader
    BD Names Chairman of Board
    Interplex Acquires OCP Group
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Adare Pharma Solutions Opens New Small-Scale Lab
    Stevanato Group Launches After-sales Service Offering
    X-Chem Acquires IntelliSyn and AviSyn
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    The Estée Lauder Companies Announces Game-Changing Sustainability Goals for Travel Retail
    Aura Introduces Customizable Hair Care
    Corpack Creates Custom Packaging for Marlies Möller Hair Care Line
    Happi

    Latest Breaking News From Happi

    Nice-Pak Receives EPA Approval for Disinfectant Wipes
    FDA Takes Major Action on Hand Sanitizers from Mexico
    Symrise Shares 2020 Sales Figures
    Ink World

    Latest Breaking News From Ink World

    Epson Partner Creates Label Applicators for Pharmaceutical Products
    Smurfit Kappa Sets New Sustainability Targets with Better Planet 2050
    Paragon Expands Direct Mail Capabilities with Ricoh Pro VC70000
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Great Lakes Label debuts new website
    Epson partner creates label applicators for pharmaceutical products
    ACTEGA removes chemicals from laminating adhesives
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    American Made Production Equipment for Mask Manufacturers
    Kimberly-Clark Releases Q4, Full Year Results
    Freudenberg to Establish Apparel Interlining Competence Centers
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Spinal Elements' Lucent XP-Curved Expandable TLIF Gains FDA Nod
    FDA OKs OrthoSpin's 2nd Gen Robotic, Digital External Fixation System
    Nextremity Solutions Enters Supply Agreement with Fort Wayne Metals
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    North American Semiconductor Equipment Industry Posts December 2020 Billings
    First Solar Signs Definitive Agreement to Sell US Development Platform to Leeward
    PRINTING United Alliance Announces TAGA Presents Virtual Event

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login