• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    The Changing Face of Medtech Surface Treatment

    The Totally Tubular Technologies that Support Medical Devices

    Simply Stimulating: Examining the Neurostimulation Sector

    Sensing Technology Drives the Future of Medical Care

    New and Developing Diabetes Technologies Offer 'Sweet Relief'
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Regulatory
    Financial/Business
    Top News
    Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter

    Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs

    Bronwyn Brophy Named CEO at Vitrolife AB

    TRIMEDX Revamps its Management Team

    Illumina Releases Cloud-Based Software for Next-Gen Sequencing
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    The Changing Face of Medtech Surface Treatment

    The Totally Tubular Technologies that Support Medical Devices

    Simply Stimulating: Examining the Neurostimulation Sector

    Sensing Technology Drives the Future of Medical Care

    New and Developing Diabetes Technologies Offer 'Sweet Relief'
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Timeline Mystery for Updated EtO Rules

    An Update on Hospital Trends Post-Pandemic

    Don’t Fear the Audit: Benefits of Good Quality Practices

    Understanding the FDA’s Standards & Conformity Assessment Program

    Medtech Divestitures Are Good for Medtech Innovation
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Arthur G. Russell Co. Inc., The

    Providence Enterprise USA Inc.

    NDH Medical Inc.

    Forefront Medical Technology

    LEMO USA Inc.
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Designing for Manufacturing: 5 Common Startup Mistakes (and How to Avoid Them)

    5 Challenges Medtech Must Address to Transform Health Care

    3D Printing Medical Devices Revolutionized Manufacturing

    5 Current Trends in Medical Device Security

    How Advanced Sensors Improve Design & Functionality of Respiratory Care Equipment
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Arthur G. Russell Co. Inc., The

    Providence Enterprise USA Inc.

    NDH Medical Inc.

    Forefront Medical Technology

    LEMO USA Inc.
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • eBook
    • Resources
    • Podcasts
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Draper Makes Advances in Extracorporeal Membrane Oxygenation

    Develops artificial lung technology with $4.9 million army grant.

    Draper Makes Advances in Extracorporeal Membrane Oxygenation
    The American Society for Artificial Internal Organs recently recognized Draper’s microfluidic blood oxygenator research by naming it the Top Pulmonary Abstract of 2021. Image courtesy of Draper.
    08.04.21
    Artificial lung assist devices have been called life-savers for people who suffer respiratory failure. But such devices carry potential risks, including blood clots, bleeding and sepsis. The answer for improving a device’s function while reducing side effects may lie in engineering it so that it more closely mimics the human lung.
     
    Draper has done just that, making advances in an artificial lung technology called extracorporeal membrane oxygenation, or ECMO. During ECMO, blood is drawn from the patient’s vascular system and circulated outside the body by a mechanical pump through an oxygenator and heat exchanger. Carbon dioxide (CO2) is removed and oxygen-saturated blood is returned to the body.
     
    In spite of decades of advances, ECMO still suffers from limitations. The device can become clogged with blood clots, which diminishes the membrane’s ability to transfer oxygen and CO2. ECMO can experience inconsistent blood flow and pressure across the device, and require high levels of anticoagulant, which can cause bleeding problems. Experts agree that reducing complications will improve outcomes for ECMO patients.
     
    To develop its artificial lung technology, Draper tapped into biomimetics, an interdisciplinary field in which principles from engineering, chemistry and biology are applied to the synthesis of materials, synthetic systems and machines that have functions that mimic biological processes.
     
    Draper fabricated silicone layers, patterned with either blood channel or gas channel networks, and bonded them together with an intervening thin gas transfer membrane. The multiple sandwich structures were stacked into a three-dimensional network joined by biomimetic blood distribution manifolds to produce a fully 3D, physiologically inspired blood circuit.
     
    Draper researchers tested the multilayer, microfluidic blood oxygenator at blood flow rates approaching clinically relevant levels. They found that a device coated with anticoagulant significantly decreased thrombus accumulation, and helped to stabilize blood pressure, compared to a device without the coating. In an upcoming paper, Draper reports their oxygenator operated at blood flow rates up to 400 milliliters per minute, the highest ever achieved in a complex microfluidic device.
     
    Overall, Draper’s device maintained critical dimensions such as gas transfer membrane thickness and blood channel geometries, and controlled levels of fluid shear within narrow ranges throughout the cartridge. These design features allowed the device to improve upon a nagging performance issue with ECMO, where contact of blood proteins with artificial surfaces, such as the membrane of the oxygenator or tubing, can cause blood clotting.
     
    Engineer Joe Santos helped design the device, called BLOx. “There is a critical need for low prime-volume, lower flow respiratory support devices. There is also an urgent requirement for simpler, safer and more portable ECMO technologies for treatment of injuries in remote locations, such as battlefields and natural disaster sites. Draper’s technology can transform the way ECMO is being done today,” Santos said.
     
    Jeff Borenstein has been working on biomimetic microfluidic oxygenators for more than a decade at Draper. “We believe microfluidic oxygenators have emerged as a potential promising avenue for improving the efficiency and safety of ECMO. Despite wide use, ECMO is limited in its accessibility because it is extremely complex and difficult to administer. We think our approach is simpler and safer, and will lead to wider use,” Borenstein said.
     
    The American Society for Artificial Internal Organs recently recognized the microfluidic blood oxygenator research by naming it the Top Pulmonary Abstract of 2021.
     
    This work was funded by the U.S. Army Medical Research Acquisition Activity and supported by the U.S. Army through the Peer Reviewed Medical Research Program under award number W81XWH1910518. Draper’s four-year, $4.9 million award is scheduled to run through July 2022. Opinions, interpretations, conclusions, and recommendations are those of the author, and are not necessarily endorsed by the U.S. Army Medical Research Acquisition Activity.
    Suggested For You
    MEDICAL & BIOTECH MANUFACTURING MEDICAL & BIOTECH MANUFACTURING
    Lee Company, The Lee Company, The
    JK Medirise-Disposable Medical Device Company JK Medirise-Disposable Medical Device Company
    Brosseau Consulting LLC Brosseau Consulting LLC
    sfm medical devices GmbH sfm medical devices GmbH
    Teleflex Medical OEM Teleflex Medical OEM
    Junkosha USA Inc. Junkosha USA Inc.
    Cobalt Polymers Cobalt Polymers
    BMP Medical - Delivering Custom Plastics Manufactured Solutions BMP Medical - Delivering Custom Plastics Manufactured Solutions
    High Tech Turning Co. Inc. High Tech Turning Co. Inc.
    Breakthrough Device Designation Granted for New Neuromodulation Platform Breakthrough Device Designation Granted for New Neuromodulation Platform
    Hyperfine Names Paykel, Teisseyre to Executive Leadership Roles Hyperfine Names Paykel, Teisseyre to Executive Leadership Roles
    Accu-Tube Appoints Matthew Haddle as CEO Accu-Tube Appoints Matthew Haddle as CEO
    First CellFX Procedure Performed in Canada First CellFX Procedure Performed in Canada
    Turner Imaging Systems Announces International Expansion Turner Imaging Systems Announces International Expansion

    Related Literature / Brochures

    • MEDICAL & BIOTECH MANUFACTURING

      ISO 13485:2016 • FDA Registered

    • Lee Company, The

      ...
      Gillian Russo, Media Manager 11.17.22

    • JK Medirise-Disposable Medical Device Company

      ...
      Ketan Munjani, Marketing Manager 11.17.22


    • Brosseau Consulting LLC

      ...
      Bryan Brosseau, President & Principal Consultant 11.17.22

    • sfm medical devices GmbH

      ...
      Albert Busch, Head of Marketing 11.11.22

    Loading, Please Wait..

    Trending
    • Masimo Reveals Freedom Health-Tracking Smartwatch
    • FDA OKs FemDx Medsystems' FalloView Device
    • Getinge’s Cardiosave Faces CE-Certificate Suspension From TÜV SÜD
    • Designing For Manufacturing: 5 Common Startup Mistakes (and How To Avoid Them)
    • Illumina Releases Cloud-Based Software For Next-Gen Sequencing
    Breaking News
    • Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter
    • Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs
    • Bronwyn Brophy Named CEO at Vitrolife AB
    • TRIMEDX Revamps its Management Team
    • Illumina Releases Cloud-Based Software for Next-Gen Sequencing
    View Breaking News >
    CURRENT ISSUE

    March 2023

    • Sensing Technology Drives the Future of Medical Care
    • New and Developing Diabetes Technologies Offer 'Sweet Relief'
    • Discussing Matters of Substance in Medtech Materials
    • Medical Device Testers Are Caught Up in a Whirlwind
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Wiley Eliminates Outer Carton From Packaging to Reduce Waste
    ACG Expands as Vantage Nutrition Acquires ComboCap and its Dual-Chamber Capsule Technology
    Melodea Launches New Plastic-Free Packaging Solution
    Coatings World

    Latest Breaking News From Coatings World

    AkzoNobel Appoints Ricardo Rosso as Pontiac Site Manager
    Sherwin-Williams Publishes Sustainable Packaging White Paper
    Heubach Launches Automotive Styling Shades 2027
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Q’Apel Medical Inc. Receives CE Mark for Walrus Balloon Guide Catheter
    Medinbox and Abbott Partner to Increase Efficiency in Electrophysiology Labs
    Bronwyn Brophy Named CEO at Vitrolife AB
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Evotec, BMS Expand Strategic Neurodegeneration Pact
    Regeneron, Sonoma Biotherapeutics Partner on Treg Cell Therapies
    Astellas, MIMETAS Enter Strategic Immuno-Oncology Alliance
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Millie Bobby Brown’s Florence by Mills Launches Eye-Centric Color Cosmetics Line
    Colorsmith Introduces ‘Salon-Quality’ Stylers for Men
    Panama Jack Launches Tropical Fragrances, Essential Oils & Body Mists
    Happi

    Latest Breaking News From Happi

    Kao Launches Space Shampoo Sheet
    Procter & Gamble Brings Tide ‘Loads of Hope’ Relief to Residents Affected by Deadly Tornado Outbreak in Mississippi
    Sederma Introduces Active Ingredient to Address Pigment Disorders
    Ink World

    Latest Breaking News From Ink World

    NAPIM Honors 2023 Ault, Pioneer Award Recipients
    Kodak to Showcase Prepress and Print Technologies at Print China 2023
    CPIPC Hosts Technical Dinner
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    CORLABEL invests in HP and a second GM finishing machine
    Elkem's Sean Duffy receives AWA Leadership Award
    eProductivity Software acquires Tharstern Group
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Ahlstrom Releases Sustainability Report
    Albaad Uses Upgrades Lenzing Fibers in Flushable Wipes
    Midwest Filtration, Monadnock Announce Partnership in Filtration
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Conventus Flower Ortho Appoints Jeff Culhane as COO
    Solid Growth Forecast for OTC Braces and Supports Market
    Exactech Boosts AI Expertise with Licensing Deal, Team of Scientists
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Japan Display to Acquire JOLED IP
    Graphenest, Hubron to Partner on Graphene Project
    CSEM Nominates Andreas Rickenbacher as New Chair of the Board

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login