• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    MPO's 2023 Medtech Supply Chain Survey

    Exceeding Medical Device Extrusion Expectations

    Medical Device Micromolders Discuss the 'Minor Details'

    Superior Subtractive Solutions for Machining Medtech

    Assembly & Automation Experts Share Thoughts on Medtech Trends
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Regulatory
    Financial/Business
    Top News
    Varian Buys Aspekt Solutions to Bolster Advanced Oncology Biz

    Patient Enrollment Ends in Biosense Webster's SmartfIRE Study

    New Data Shows Advantages of Rapid Medical’s COMANECI Embolization Assist Device

    Former FDA Director Joins Greenleaf Health

    Alexander D’Amico Named Chief Financial Officer at CytoSorbents
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    MPO's 2023 Medtech Supply Chain Survey

    Exceeding Medical Device Extrusion Expectations

    Medical Device Micromolders Discuss the 'Minor Details'

    Superior Subtractive Solutions for Machining Medtech

    Assembly & Automation Experts Share Thoughts on Medtech Trends
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Back to School for Medical Device Cybersecurity Training

    Driving Clinical Trial Excellence to Help Study Teams Run a Faster Relay Race

    Medtech’s Supply Chain: From Disruption to Opportunity

    Are Medtech’s Mega-Deals Gone For Good?

    Will a Skilling Gap Hinder Organizational Readiness for Medtech’s New Age of AI?
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Providence Enterprise USA Inc.

    Johari Digital Healthcare Ltd.

    NDH Medical Inc.

    Arthur G. Russell Co. Inc., The

    LEMO USA Inc.
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    How Wearables Are Changing the Way We Collect Real-World Data in Clinical Trials

    Could Medtech Ever Stop a Hospital Killer in Their Tracks?

    A One-Stop-Shop, Turnkey Solution Is Paramount for Success

    How Additive and Subtractive Manufacturing Are Revolutionizing the Medical Device Industry

    Medical Device Commercialization: It’s What, Not When, to Transfer to Manufacturing
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Providence Enterprise USA Inc.

    Johari Digital Healthcare Ltd.

    NDH Medical Inc.

    Arthur G. Russell Co. Inc., The

    LEMO USA Inc.
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • eBook
    • Resources
    • Podcasts
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Researchers Develop Hydrogel Capable of Providing Sustained Medication Release

    Delivers drugs at the cellular level and engineers tissue.

    Researchers Develop Hydrogel Capable of Providing Sustained Medication Release
    An illustration of how an engineered Q protein self-assembles to form fiber-based hydrogels at low temperature. Image courtesy of NYU Tandon.
    NYU Tandon09.18.19
    Imagine a perfectly biocompatible, protein-based drug delivery system durable enough to survive in the body for more than two weeks and capable of providing sustained medication release. An interdisciplinary research team led by Jin Kim Montclare, a professor of biomolecular and chemical engineering at the NYU Tandon School of Engineering, has created the first protein-engineered hydrogel that meets those criteria, advancing an area of biochemistry critical to not only to the future of drug delivery, but tissue engineering and regenerative medicine.
     
    Hydrogels are three-dimensional polymer networks that reversibly transition from solution to gel in response to physical or chemical stimuli, such as temperature or acidity. These polymer matrices can encapsulate cargo, such as small molecules, or provide structural scaffolding for tissue engineering applications. Montclare is lead author of a new paper in the journal Biomacromolecules, which details the creation of a hydrogel comprised of a single protein domain that exhibits many of the same properties as synthetic hydrogels. Protein hydrogels are more biocompatible than synthetic ones, and do not require potentially toxic chemical crosslinkers.
     
    "This is the first thermo-responsive protein hydrogel based on a single coiled-coil protein that transitions from solution to gel at low temperatures through a process of self-assembly, without the need for external agents," said Montclare. "It's an exciting development because protein-based hydrogels are much more desirable for use in biomedicine."
     
    The research team conducted experiments encapsulating a model small molecule within their protein hydrogel, discovering that small molecule binding increased thermostability and mechanical integrity and allowed for release over a timeframe comparable to other sustained-release drug delivery vehicles. Future work will focus on designing protein hydrogels tuned to respond to specific temperatures for various drug delivery applications.
    Related Searches
    • drug delivery
    • engineering
    • temperature
    • Assembly
    Related Knowledge Center
    • Materials
      Loading, Please Wait..

      Trending
      • Cardiosense Begins SEISMIC-HF I Heart Failure Trial
      • Danaher Names New Environmental And Applied Solutions Company Veralto
      • Exo Introduces The Exo Iris To Market
      • A New Approach To Post-Market Surveillance
      • FDA Clears LiveMetric's Wearable Blood Pressure Monitoring Tech
      Breaking News
      • Varian Buys Aspekt Solutions to Bolster Advanced Oncology Biz
      • Patient Enrollment Ends in Biosense Webster's SmartfIRE Study
      • New Data Shows Advantages of Rapid Medical’s COMANECI Embolization Assist Device
      • Former FDA Director Joins Greenleaf Health
      • Alexander D’Amico Named Chief Financial Officer at CytoSorbents
      View Breaking News >
      CURRENT ISSUE

      September 2023

      • Superior Subtractive Solutions for Machining Medtech
      • Medical Device Industry Experts' Thought on Assembly & Automation
      • Power Trip: A Discussion of Custom Medical Electronics
      • The MDR Transition: An Opportunity for Design Change?
      • View More >

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      PLT Health Solutions Granted Claims for Botanical Ingredient in Canada
      CRN Files Petition with FTC For Clarity on Health Products Compliance Guidance
      Vitafoods Europe Relocates to Barcelona Starting 2025
      Coatings World

      Latest Breaking News From Coatings World

      Tim Knavish Elected PPG Chairman and CEO
      Alabama Students Gain Real-World Experience with Internships at BASF
      AkzoNobel Names Sweet Embrace as Interpon Color of the Year 2024
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Former FDA Director Joins Greenleaf Health
      Alexander D’Amico Named Chief Financial Officer at CytoSorbents
      Moon Surgical Completes First U.S. Cases with Maestro System
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Ginkgo Bioworks, Pfizer Enter Multi-Target RNA Discovery Alliance
      WuXi Vaccines Launches Vaccines CDMO Site in China
      MilliporeSigma Launches Integrated mRNA Services
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      BASF and StitchCrew Introduce Educational Bootcamp for Indigenous Beauty Brands
      Top 10 Most Popular Fashion Designer Makeup Brands—According to Landys Chemist
      Jennifer Coolidge Collaborates with e.l.f. Cosmetics for 'Dirty Pillows' Lip Collection
      Happi

      Latest Breaking News From Happi

      Bio-Oil Launches 'Labor of Love' Campaign
      Wharton To Honor Leonard A. Lauder with Retail Excellence Award
      Extracts-Unlimited Attains Organic Certification
      Ink World

      Latest Breaking News From Ink World

      Sapphire Ink – SB Eco Series Receives Oeko-Tex Eco Passport ZDHC Level 3 Certification
      Flint Group Digital with Xeikon Present at FEFCO Technical Seminar
      R.E. Carroll Inc. Packs, Donates 400 Backpacks to Students
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Kodak launches PRINERGY 10.0
      UPM Raflatac receives new approval for linerless label printing
      UK flexo industry comes together at Apex LIVE
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      Ana Fraisse Joins The American Cleaning Institute
      Weekly Recap: Soft N' Dry Seeks to Expand Private Label Roll Out, Albis Completes Work on Line
      Lenzing Earns EU Ecolabel at Indonesian Plant
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      ONWARD Completes First-in-Human for ARC-IM to Restore Upper Extremity Function
      Michael S. Aronow Installed as AOFAS President
      Abyrx's MONTAGE Settable Bone Putty Cleared for Cardiothoracic Surgery
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      PPG and Flō-Optics Enter Exclusive Supplier Agreement
      SEMI North America Advisory Board Adds New Members
      Nhat Tin Logistics Enhances Operations with Zebra Technologies

      Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login