• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Electrifying Healthcare: A Look at Electronics Manufacturing Services for Medtech

    Smooth Operator: Addressing Machining's Talent Gap

    Valued R&D: The Transformation of Medical Device Research and Development

    Additive Manufacturing: A Tool for Driving Innovation

    Layering Metal: Additive Manufacturing in Medtech
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    Robotic Sensor Can Spot Reproductive Health Problems in Real-Time

    First Motor-Controlled Heart Valves Implanted in Europe

    Micro Interventional Devices and Neovasc Settle TMVR Lawsuit

    FDA Clears New Soft Tissue Visualization for ViewRay's MRIdian System

    IZI Medical Products Acquires Quick-Core Biopsy, Breast Localization Needle Assets From Cook Medical
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Electrifying Healthcare: A Look at Electronics Manufacturing Services for Medtech

    Smooth Operator: Addressing Machining's Talent Gap

    Valued R&D: The Transformation of Medical Device Research and Development

    Additive Manufacturing: A Tool for Driving Innovation

    Layering Metal: Additive Manufacturing in Medtech
    Top 30 Medical Device Companies
    Top Top 30
    Top 30 Global Medical Device Companies

    1. Medtronic plc

    2. Johnson & Johnson

    3. GE Healthcare

    4. Royal Philips
    Market Data
    Datawatch Column
    Salary Survey
    White Papers
    Top Research
    Discerning Medtech’s Path in 2019

    Disrupting the Outsourcing Model

    Election Impact and the Beginning of the 116th Congress

    Is Your Packaging Provider Prepared If Disaster Strikes?

    A Primer for Manufacturers Adjusting to Value-Based Healthcare
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Propel

    PTI Engineered Plastics Inc.

    Forefront Medical Technology

    Marox Corporation

    Pulse Systems
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Help Wanted

    Is VR the Solution for Addressing Chronic Pain?

    Design Sophisticate

    Sintered or Expanded—Which PTFE Is Best Suited for Your Device?

    Best Practices Spotlight: How to Grow Your Products Globally
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Propel

    Spectrum Plastics Group

    K-Tube Technologies

    PTI Engineered Plastics Inc.

    Forefront Medical Technology
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Salary Survey
      • Market Data
      • Datawatch Column
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Micromotors Deliver Oral Vaccines

    Researchers coated magnesium micromotors with red blood cell membranes to help them stick to intestinal mucus.

    Related CONTENT
    • A Pill for Delivering Biomedical Micromotors
    • New Blood Test Spots Early Stage Pancreatic Cancer
    • Irritation Testing Is Becoming Less Irritating
    • Mini Magnetic Swimming Devices to Transform Diagnostics and Drug Delivery
    • New Method Uses a Drop of Blood to Monitor Lung Cancer Treatment
    American Chemical Society02.11.19
    Vaccines have saved millions of lives, but nobody likes getting a shot. That's why scientists are trying to develop oral vaccines for infectious diseases. But to be effective, the vaccine must survive digestion and reach immune cells within the intestinal wall. Now, researchers reporting in the ACS journal Nano Letters have developed oral vaccines powered by micromotors that target the mucus layer of the intestine.
     
    In addition to avoiding needles, oral vaccines can generate a broader immune response by stimulating immune cells within the mucus layer of the intestine to produce a special class of antibody called immunoglobulin A (IgA). Joseph Wang, Liangfang Zhang and colleagues wondered if they could use magnesium particles as tiny motors to deliver an oral vaccine against the bacterial pathogen Staphylococcus aureus. When coated over most of their surfaces with titanium dioxide, magnesium microparticles use water as fuel to generate hydrogen bubbles that power their propulsion.
     
    To develop the oral vaccine, the researchers coated magnesium micromotors with red blood cell membranes that displayed the Staphylococcal α-toxin, along with a layer of chitosan to help them stick to the intestinal mucus. Then, they added an enteric coating that protects drugs from the acidic conditions of the stomach. When given orally to mice, the micromotors safely passed through the stomach, and then the enteric coating dissolved, activating the motors. Imaging of mice that had been given the vaccine showed that the micromotors accumulated in the intestinal wall much better than non-motorized particles. The micromotors also stimulated the production of about ten times more IgA antibodies against the Staphylococcal α-toxin than the static particles.
    Related Searches
    • coating
    • power
    • staphylococcus aureus
    • imaging
    Suggested For You
    New Skin Test Detects Prion Infection Before Symptoms Appear New Skin Test Detects Prion Infection Before Symptoms Appear
    Microneedle Device Could Provide Quicker Diagnoses of Major Illnesses Microneedle Device Could Provide Quicker Diagnoses of Major Illnesses
    Simple Urine Test Could Diagnose Bacterial Pneumonia Simple Urine Test Could Diagnose Bacterial Pneumonia
    3D Bioprinting Technique Creates Lifelike Tissues from Natural Materials 3D Bioprinting Technique Creates Lifelike Tissues from Natural Materials
    Deciphering Dosage: A Focus on Combination Products Deciphering Dosage: A Focus on Combination Products
    Nanodevice Delivers Immunotherapy Without Side Effects Nanodevice Delivers Immunotherapy Without Side Effects
    New Method Uses a Drop of Blood to Monitor Lung Cancer Treatment New Method Uses a Drop of Blood to Monitor Lung Cancer Treatment
    Mini Magnetic Swimming Devices to Transform Diagnostics and Drug Delivery Mini Magnetic Swimming Devices to Transform Diagnostics and Drug Delivery
    Irritation Testing Is Becoming Less Irritating Irritation Testing Is Becoming Less Irritating
    New Blood Test Spots Early Stage Pancreatic Cancer New Blood Test Spots Early Stage Pancreatic Cancer
    A Pill for Delivering Biomedical Micromotors A Pill for Delivering Biomedical Micromotors

    Related Breaking News

    • Diagnostics | Electronics | Patient Monitoring
      Robotic Sensor Can Spot Reproductive Health Problems in Real-Time

      Robotic Sensor Can Spot Reproductive Health Problems in Real-Time

      The sensor measures hormones that affect fertility, sexual development, and menstruation more quickly and cheaply than current methods.
      Imperial College London 02.21.19

    • Cardiovascular | Surgical
      First Motor-Controlled Heart Valves Implanted in Europe

      First Motor-Controlled Heart Valves Implanted in Europe

      The self-expanding aortic valves (CENTERA) were implanted at Mainz University Medical Center.
      Universitat Mainz 02.21.19

    • Cardiovascular | Surgical
      Micro Interventional Devices and Neovasc Settle TMVR Lawsuit

      Micro Interventional Devices and Neovasc Settle TMVR Lawsuit

      Neovasc will pay MID $3M upfront over 2 years, and a 1.3 percent royalty on commercial sales of its Tiara device.
      PR Newswire 02.21.19


    • Diagnostics
      FDA Clears New Soft Tissue Visualization for ViewRay

      FDA Clears New Soft Tissue Visualization for ViewRay's MRIdian System

      Proprietary technology from ViewRay enables imaging and treatment enhancements.
      PR Newswire 02.21.19

    • IZI Medical Products Acquires Quick-Core Biopsy, Breast Localization Needle Assets From Cook Medical

      IZI Medical Products Acquires Quick-Core Biopsy, Breast Localization Needle Assets From Cook Medical

      Deal is IZI Medical's third add-on acquisition in the last 19 months.
      Business Wire 02.21.19

    • Medidata Appoints Industry Leader as Executive Vice President of Digital and AI Solutions

      Medidata Appoints Industry Leader as Executive Vice President of Digital and AI Solutions

      New hire brings 19 years of experience in healthcare technology to the position.
      Business Wire 02.21.19


    • Senseonics Appoints Chief Financial Officer

      Senseonics Appoints Chief Financial Officer

      New hire has nearly 25 years of experience in financial leadership roles.
      Business Wire 02.21.19

    • Digital Health | Patient Monitoring | Software & IT
      Novo Nordisk Digital Insulin Pen Now Compatible with Abbott

      Novo Nordisk Digital Insulin Pen Now Compatible with Abbott's FreeStyle Libre CGM

      Insulin data can be shared between Novo Nordisk connected insulin pens and digital health tools compatible with FreeStyle Libre products.
      Abbott Laboratories 02.20.19

    • Surgical
      FDA Clears Intuitive Surgical

      FDA Clears Intuitive Surgical's Lung Cancer Biopsy Robot

      Flexible robotic catheter helps physicians reach nodules in the peripheral lung.
      Intuitive Surgical 02.20.19


    • NxStage Must Divest Bloodline Tubing Biz to B. Braun to Complete Fresenius Merger

      NxStage Must Divest Bloodline Tubing Biz to B. Braun to Complete Fresenius Merger

      FTC’s complaint alleges the proposed merger would harm competition in the U.S. market for dialysis bloodline tubing sets.
      Federal Trade Commission (FTC) 02.20.19

    • Cardiovascular
      Edwards’ PASCAL Transcatheter System Receives CE Mark

      Edwards’ PASCAL Transcatheter System Receives CE Mark

      The PASCAL system is designed for effective reduction of mitral regurgitation while respecting the native anatomy.
      Edwards Lifesciences Corporation 02.20.19

    • Patient Monitoring
      FDA OKs Philips

      FDA OKs Philips' DigitalDiagnost C90 Digital Radiography System

      The ceiling-mounted system touts the industry’s first live camera image at the tube head.
      Philips 02.20.19

    • Neurological
      Robotic Aid to Drug-Free Depression Treatment Wins FDA Nod

      Robotic Aid to Drug-Free Depression Treatment Wins FDA Nod

      MagVenture TMS Therapy is an effective, non-invasive option for the large number of patients not responding to antidepressants.
      PR Newswire 02.20.19

    • ResMed and Fisher & Paykel Settle Patent Case

      ResMed and Fisher & Paykel Settle Patent Case

      The settlement involves no payment or admission of liability by either side.
      Business Wire 02.20.19

    • Cardiovascular
      Powering a Pacemaker with a Patient

      Powering a Pacemaker with a Patient's Heartbeat

      The device was successfully tested in pigs.
      American Chemical Society 02.20.19


    Breaking News
    • Robotic Sensor Can Spot Reproductive Health Problems in Real-Time
    • First Motor-Controlled Heart Valves Implanted in Europe
    • Micro Interventional Devices and Neovasc Settle TMVR Lawsuit
    • FDA Clears New Soft Tissue Visualization for ViewRay's MRIdian System
    • IZI Medical Products Acquires Quick-Core Biopsy, Breast Localization Needle Assets From Cook Medical
    View Breaking News >
    CURRENT ISSUE

    January/February 2019

    • Electrifying Healthcare: A Look at Electronics Manufacturing Services for Medtech
    • Smooth Operator: Addressing Machining's Talent Gap
    • Valued R&D: The Transformation of Medical Device Research and Development
    • Additive Manufacturing: A Tool for Driving Innovation
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • privacy policy
    • term and condition
    • about us
    • contact us

    follow us

    Subscribe

    magazines

    Image
    Image
    Image
    Image
    Image
    Image
    Image
    Image
    Image
    Image
    Image

    Copyright © 2019 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login