• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    OEMs Seek Molders Offering Timely Techniques

    Robotic Surgery: Cutting Through to the Latest

    Packaging, Sterilization Considerations Go Part and Parcel with Product Development

    Cybersecurity Challenges Leave Medical Device Makers Insecure

    OEMs Are Demanding Designs that Challenge Suppliers
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Regulatory
    Financial/Business
    Top News
    MPO's Most Read Stories This Week—June 25

    Magnetic Insight Announces $17 Million in Series B Funding

    BreatheSuite Adds Brad Fluegel to its Board

    Labcorp Launches At-Home Collection Device for Diabetes Risk Testing

    Thirona, Free Flow Medical Partner on COPD Solutions
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    OEMs Seek Molders Offering Timely Techniques

    Robotic Surgery: Cutting Through to the Latest

    Packaging, Sterilization Considerations Go Part and Parcel with Product Development

    Cybersecurity Challenges Leave Medical Device Makers Insecure

    OEMs Are Demanding Designs that Challenge Suppliers
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Theranos Fraud Trial, Part II: The Blame Game Continues

    An Update on Surgical Robotics

    Letting the Light In: How Failure Analysis is the Cornerstone of Success

    Three Talent Strategies to Attract High-Demand Skills

    The Advantages of Bioburden Screening for Sterilization Validation
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Concise Engineering

    Xact Wire EDM Corp.

    Cirtec Medical

    Arthur G. Russell Co. Inc., The

    Trademark Plastics Inc.
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    The Power of Leveraging Customer Relationships

    Cost Effective & Efficient Wire EDM Techniques

    How MedTech Professionals Can Help Combat Physician Burnout

    How to Optimize Manufacturing Lines and Choose Which Machines to Buy

    How Are Hypodermic Needles Made?
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Concise Engineering

    Xact Wire EDM Corp.

    Cirtec Medical

    Arthur G. Russell Co. Inc., The

    Trademark Plastics Inc.
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • eBook
    • Resources
    • Podcasts
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Study: Surgical Stapler Design May Reduce Lung Surgery Complication

    Greater than two-to-one difference in thoracic surgery air leak incidence.

    Study: Surgical Stapler Design May Reduce Lung Surgery Complication
    Using a novel Physiologic Lung Model (PLM) that simulates intraoperative and postoperative breathing, researchers for the first time were able to directly observe, track and quantify staple-line air leaks from 110 sets of excised and stapled porcine lungs.
    Related CONTENT
    • BD Names Christopher DelOrefice as EVP and CFO
    • Ethicon Launches Novel Buttressing Device
    • FDA Grants Breakthrough Device Designation for Ethicon’s Microwave Ablation Technology
    • Johnson & Johnson
    • Ethicon Compares Gastric Bypass Surgery to Pharmacotherapy in Treating CKD
    Ethicon02.01.19
    A recent study has found significant differences between surgical stapler technologies when it comes to the impact the devices have on the rate of air leaks, one of the most common complications associated with lobectomies, a type of thoracic surgery to treat lung cancer. The research was funded by Ethicon, part of Johnson & Johnson Medical Devices Companies, and is being announced this week at the 2019 Society of Thoracic Surgeons (STS) Annual Meeting.
     
    Using a novel Physiologic Lung Model (PLM) that simulates intraoperative and postoperative breathing, researchers for the first time were able to directly observe, track and quantify staple-line air leaks from 110 sets of excised and stapled porcine lungs. Graduated staple lines, or those of varying heights, created with Medtronic’s ENDO GIA with Tri-Staple Technology (Tri-Staple) had more than twice the rate (44 percent vs. 20 percent) of staple-line air leaks under modeled physiologic breathing conditions as Ethicon’s ECHELON FLEX GST System (GST), a stapler system that surgeons use to deploy uniform closed staple line heights, according to the study published online in the peer-reviewed journal, Medical Devices: Evidence and Research in December.1
     
    In addition to finding higher air leak rates for graduated staple designs, postoperative, or natural breathing conditions, as simulated with negative pressure ventilation, were also independently associated with a higher incidence and magnitude of air leaks than positive pressure ventilation, which was used to replicate ventilator-assisted breathing conditions during surgery.
     
    “Staple design and breathing modality are two important variables that may impact air leaks, one of the biggest challenges we face in thoracic surgery,” said Seth D. Force, M.D., lead study author and Chief, General Thoracic Surgery at Emory Healthcare in Atlanta, Ga. “Our findings suggest that lungs, and any associated staple lines, behave differently under intraoperative and postoperative ventilation, which may necessitate different staple design considerations and more rigorous testing of future staplers.”
     
    Based on their findings, researchers hypothesize that graduated staple lines in the thinner tissue regions of the lung (outer row) do not sufficiently compress the tissue to prevent air leaks, which have been shown to occur in about one-quarter of lobectomies and are associated with longer hospitalizations, higher costs and nearly double the risk of in hospital mortality.2 Differences in stapler design and how each device exerts force on tissue during stapling may also contribute to air leaks, the study authors also concluded.
     
    “The evidence continues to mount that not all surgical staplers are created equally when it comes to reducing costly and serious complications associated with thoracic surgery,” said Edmund Kassis, M.D., a study co-author and Senior Medical Director for Thoracic Surgery at Ethicon. “The selection of surgical stapler could lead to better outcomes, lower costs and reduced length of stay for patients. Surgeons have an important choice to make.”
     
    Another recent real-world evidence study on air leak complications adds to previous research, published in Advances in Therapy, that found Ethicon’s ECHELON FLEX Powered Staplers were associated with reduced bleeding complications, hospital costs, and length of stay in video-assisted thoracoscopic surgery (VATS) lobectomy compared to non-powered staplers manufactured by Medtronic.3 Bleeding complications, another complication associated with thoracic surgery, occur in 2 to 10 percent of procedures.4,5
     
    About the Physiologic Lung Model (PLM)
    To better understand air leaks, Ethicon, in partnership with leading experts in thoracic surgery, developed a novel Physiologic Lung Model (PLM) to evaluate and quantify air leaks by incidence and volume. Unlike any previous benchtop model, the PLM approximates clinical conditions by simulating two breathing modalities in ex vivo lung tissue -- ventilated breathing and physiologic, or natural, breathing conditions, as well as enabling functional properties of the organ, such as gas exchange. No other model has the capability to simulate patients’ physiologic breathing, allowing air leaks to be examined in a simulated post-operative setting.6 The PLM was first described in “Ex Vivo Modeling of Perioperative Air Leaks in Porcine Lungs," an article that was published in the peer-reviewed journal, IEEE Transactions on Biomedical Engineering, in March 2018.  
     
    References
    1 Chad E Eckert, Jason L Harris, Jordan B Wong, Suzanne Thompson, Edmund S Kassis, Masahiro Tsuboi, Harald C Ott, Seth Force. – “Preclinical quantification of air leaks in a physiologic lung model: effects of ventilation modality and staple. Medical Devices: Evidences and Research. Dec. 14, 2018; Volume 2018:11 Pages 433—442 https://www.dovepress.com/articles.php?article_id=43056
    2 Yoo A, Ghosh SK, Danker W. et al. Burden of air leak complications in thoracic surgery estimated using a national hospital billing database. ClinicoEconomics and Outcomes Research. 2017;9:378-383.
    3 Miller DL, et al. Impact of powered and tissue-specific endoscopic stapling technology on clinical and economic outcomes of video-assisted thoracic surgery lobectomy procedures: a retrospective, observational study. In press February 13, 2018.
    4 Kent M, et al. Open, video-assisted thoracic surgery, and robotic lobectomy: review of a national database. Ann Thorac Surg. 2014;97:236-444. 
    5 Based on Ethicon (2016) internal analysis of data from 26,955 lobectomy procedures captured in Premier Perspective database for period 2008-2014. 
    6 Klassen C, Eckert CE, Wong J. et al. Ex Vivo Modeling of Perioperative Air Leaks in Porcine Lungs. IEEE Transactions on Biomedical Engineering (2018). https://ieeexplore.ieee.org/document/8325303/
    Related Searches
    • Medical Devices
    • technology
    • track
    • research
    Related Knowledge Center
    • Surgical
    Suggested For You
    BD Names Christopher DelOrefice as EVP and CFO BD Names Christopher DelOrefice as EVP and CFO
    Ethicon Launches Novel Buttressing Device Ethicon Launches Novel Buttressing Device
    FDA Grants Breakthrough Device Designation for Ethicon’s Microwave Ablation Technology FDA Grants Breakthrough Device Designation for Ethicon’s Microwave Ablation Technology
    Johnson & Johnson Johnson & Johnson
    Ethicon Compares Gastric Bypass Surgery to Pharmacotherapy in Treating CKD Ethicon Compares Gastric Bypass Surgery to Pharmacotherapy in Treating CKD
    Valued R&D: The Transformation of Medical Device Research and Development Valued R&D: The Transformation of Medical Device Research and Development
     CERENOVUS Launches Global Registry to Study Stroke-Inducing Blood Clots Removed by Thrombectomy CERENOVUS Launches Global Registry to Study Stroke-Inducing Blood Clots Removed by Thrombectomy
    J&J, Apple Seek to Improve AFib Outcomes J&J, Apple Seek to Improve AFib Outcomes
    Largest Medical AI Imaging Technology Platform Adds Capabilities to Speed Radiology Reports Largest Medical AI Imaging Technology Platform Adds Capabilities to Speed Radiology Reports
    Microneedle Patch Glucose Monitor Proves Virtually Painless and More Accurate Microneedle Patch Glucose Monitor Proves Virtually Painless and More Accurate
    'Stentrode' Developed for Brain Treatments Without Major Surgery
    RSNA News: University of Vermont Professor Joins RSNA Board of Directors RSNA News: University of Vermont Professor Joins RSNA Board of Directors
    The Future of Medical Device Design Companies The Future of Medical Device Design Companies
    Cagent Vascular Appoints Medical Device Industry Veteran as Board Chairman Cagent Vascular Appoints Medical Device Industry Veteran as Board Chairman
    LuxCath Appoints Chief Technology Officer LuxCath Appoints Chief Technology Officer

    Related Breaking News

    • BD Names Christopher DelOrefice as EVP and CFO

      BD Names Christopher DelOrefice as EVP and CFO

      DelOrefice joins the company from Johnson & Johnson.
      BD 08.12.21

    • Surgical
      Ethicon Launches Novel Buttressing Device

      Ethicon Launches Novel Buttressing Device

      An easy-to-use staple line reinforcement device for bariatric, thoracic, and general surgery.
      Ethicon 09.18.20

    • Surgical
      FDA Grants Breakthrough Device Designation for Ethicon’s Microwave Ablation Technology

      FDA Grants Breakthrough Device Designation for Ethicon’s Microwave Ablation Technology

      Provides a minimally invasive option for soft tissue lesions.
      Ethicon 07.30.20


    • Johnson & Johnson

      Johnson & Johnson

      ...
      07.21.20

    • Chronic Disease | Surgical
      Ethicon Compares Gastric Bypass Surgery to Pharmacotherapy in Treating CKD

      Ethicon Compares Gastric Bypass Surgery to Pharmacotherapy in Treating CKD

      Shows efficacy of bariatric surgery in treating major diseases tied to obesity.
      Ethicon 07.20.20


    Trending
    • Intermountain Healthcare & Siemens Healthineers Open 3 Tellica Outpatient Imaging Centers
    • 5 Ways Plastics Revolutionized The Healthcare Industry
    • Magnetic Insight Announces $17 Million In Series B Funding
    • Thermo Fisher Scientific, Bio-Techne Develop Kidney Rejection Test
    • The Power Of Leveraging Customer Relationships
    Breaking News
    • MPO's Most Read Stories This Week—June 25
    • Magnetic Insight Announces $17 Million in Series B Funding
    • BreatheSuite Adds Brad Fluegel to its Board
    • Labcorp Launches At-Home Collection Device for Diabetes Risk Testing
    • Thirona, Free Flow Medical Partner on COPD Solutions
    View Breaking News >
    CURRENT ISSUE

    June 2022

    • OEMs Seek Molders Offering Timely Techniques
    • Robotic Surgery: Cutting Through to the Latest
    • Packaging, Sterilization Considerations Go Part and Parcel with Product Development
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Florida Food Products Acquires Javo
    Roquette Launches Nutralys Rice Protein
    New IADSA Chair Lauds Explorations of Supplementation in Healthcare Policy
    Coatings World

    Latest Breaking News From Coatings World

    The Southern Society for Coatings Technology's 84th Annual Technical Conference A Success
    PPG to Showcase Specialty Automotive, Aerospace Adhesives, Sealants at Adhesives & Bonding Expo
    PPG’s New Paint for a New Start Initiative to Transform 25-plus Schools Worldwide
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most Read Stories This Week—June 25
    Magnetic Insight Announces $17 Million in Series B Funding
    BreatheSuite Adds Brad Fluegel to its Board
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Pierre Fabre and Lonza Enter Manufacturing Agreement
    MasterControl and Elemental Machines Form Biomanufacturing Partnership
    Qosina Strengthens Aseptic Capabilities
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Benefit Exec Joins Madison Reed's Board
    Peroni & Ellis Brooklyn Launch Fragrance Collection Inspired by Italian Spritz Cocktails
    Rhode Is Trending for June, Trendalytics Says
    Happi

    Latest Breaking News From Happi

    Spate’s Nose for the Latest Beauty Trends Says The Skunk Stripe, Collagen Serum and Waterproof Eyeshadow are Top of Mind for Consumers this Summer
    A Suitor Emerges for Revlon, SK Capital’s New Dealmaker & P&G’s Indoor Air Quality Efforts
    Wonder Curl Wins GlossWire's GlossPitch Competition
    Ink World

    Latest Breaking News From Ink World

    Weekly Recap: INX’s VC Fund, Screen Industry and Ball Top This Week’s News
    British Coatings Federation Posts Online History
    Orion Announces Price Increases, Reduced Payment Terms
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    PCMC teams with IGT, Fujifilm makes big announcement and more
    Loftware recognized as 'AIDC Company of the Year'
    Schreiner MediPharm highlights sustainability of Needle-Trap technology
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: SWM and Neenah Introduce Mativ Inc., Avgol honored for Biotransformation Technology & More
    Tranzonic Names VP of Supply Chain
    Ontex Climate Action Targets Approved by Science-Based Targets Initiative
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—June 25
    3Spine Inc. Receives IDE Approval for U.S. Pivotal Clinical Trial
    Volume-Based Procurement to Reduce Chinese Orthopedic Market Value
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: eMagin, Applied Materials, and Schott Top This Week’s Stories
    NREL Names Jennifer Logan to Leadership Team as CFO
    National Grid Renewables Orders 2 GW of First Solar Modules

    Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login