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    Breaking News

    Boston Scientific Closes Symetis Acquisition

    Expands company's structural heart portfolio; increases offerings for treatment of patients with valvular heart disease.

    Boston Scientific Closes Symetis Acquisition
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    PR Newswire05.16.17
    Boston Scientific Corporation announced the close of its acquisition of Symetis SA, a privately-held Swiss structural heart company focused on minimally-invasive transcatheter aortic valve implantation (TAVI) devices.
     
    With the completion of the acquisition, Boston Scientific will immediately begin selling the ACURATE TA and ACURATE neo/TF valve1 systems in Europe and in other geographies outside of the United States, and Symetis will become part of the Boston Scientific Interventional Cardiology division. 
     
    The two organizations announced a definitive agreement on March 30, 2017 for Boston Scientific to acquire the Symetis business for $435 million in cash.
     
    "Adding the ACURATE family of valve products to our structural heart portfolio presents us with the opportunity to provide two distinctly different but complementary TAVI platforms enabling implanting physicians and hospitals to treat the broadest range of patients and aortic valve anatomies," said Ian Meredith, M.D., executive vice president and global chief medical officer, Boston Scientific. "This valve offering, along with our left atrial appendage closure device, uniquely position us to advance structural heart solutions for patients while fueling continued growth for the company." 
     
    As with the company's cornerstone LOTUS Valve System2 platform, the ACURATE valves are designed to treat patients suffering from severe and symptomatic aortic valve stenosis, who are considered at high risk for surgical valve replacement. Instead of open heart surgery, the replacement valve is delivered via a transcatheter percutaneous delivery system. The ACURATE platform is recognized for its ease of use during valve implantation. 
     
    Results for the ACURATE neo/TF valve in the SAVI-TF Registry will be presented today as a late breaking clinical trial at the annual EuroPCR Scientific Congress in Paris. This European post-market study assesses the primary endpoint of all-cause mortality at 30 days as well as VARC-23 clinical endpoints through one year in 1,000 patients.
     
    Boston Scientific expects to continue the development of the ACURATE neo/AS4 next-generation valve system that is currently in a clinical trial intended to support a future CE mark application.
     
    On an adjusted basis, the transaction is expected to be immaterial in 2017, slightly accretive in 2018, and increasingly accretive thereafter. The transaction is expected to be less accretive (or slightly dilutive, as the case may be) on a GAAP basis, due to amortization expense and transaction and integration costs.
     
    References
    1The ACURATE TA and ACURATE neo/TF valve systems are not available for use or sale in the US. 
    2The LOTUS valve is currently not available for use or sale. 
    3Valve Academic Research Consortium-2 (VARC-2) criteria are standardized endpoints for TAVI outcomes.
    4The ACURATE neo/AS valve system is not available for use or sale.
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    CURRENT ISSUE

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    • Pharmaceutical Focus: A Look at Combination Products
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