Roboticists are envisioning a future in which soft, animal-inspired robots can be safely deployed in difficult-to-access environments, such as inside the human body or in spaces that are too dangerous for humans to work, in which rigid robots cannot currently be used. Centimeter-sized soft robots have been created, but thus far it has not been possible to fabricate multifunctional flexible robots that can move and operate at smaller size scales.
 
A team of researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering, Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), and Boston University now has overcome this challenge by developing an integrated fabrication process that enables the design of soft robots on the millimeter scale with micrometer-scale features. To demonstrate the capabilities of their new technology, they created a robotic soft spider—inspired by the millimeter-sized colorful Australian peacock spider—from a single elastic material with body-shaping, motion, and color features. The study is published in Advanced Materials.
 
“The smallest soft robotic systems still tend to be very simple, with usually only one degree of freedom, which means that they can only actuate one particular change in shape or type of movement,” said Sheila Russo, Ph.D., co-author of the study. Russo helped initiate the project as a Postdoctoral Fellow in Robert Wood’s group at the Wyss Institute and SEAS and now is Assistant Professor at Boston University. “By developing a new hybrid technology that merges three different fabrication techniques, we created a soft robotic spider made only of silicone rubber with 18 degrees of freedom, encompassing changes in structure, motion, and color, and with tiny features in the micrometer range.”
 
Wood, Ph.D., is a core faculty member and co-leader of the Bioinspired Soft Robotics platform at the Wyss Institute and the Charles River Professor of Engineering and Applied Sciences at SEAS. “In the realm of soft robotic devices, this new fabrication approach can pave the way towards achieving similar levels of complexity and functionality on this small scale as those exhibited by their rigid counterparts. In the future, it can also help us emulate and understand structure-function relationships in small animals much better than rigid robots can,” he said.
 
In their Microfluidic Origami for Reconfigurable Pneumatic/Hydraulic (MORPH) devices, the team first used a soft lithography technique to generate 12 layers of an elastic silicone that together constitute the soft spider’s material basis. Each layer is precisely cut out of a mold with a laser-micromachining technique, and then bonded to the one below to create the rough 3D structure of the soft spider.
 
Key to transforming this intermediate structure into the final design is a pre-conceived network of hollow microfluidic channels that is integrated into individual layers. With a third technique known as injection induced self-folding, pressurized one set of these integrated microfluidic channels with a curable resin from the outside. This induces individual layers, and with them also their neighboring layers, to locally bend into their final configuration, which is fixed in space when the resin hardens. This way, for example, the soft spider’s swollen abdomen and downward-curved legs become permanent features.
 
“We can precisely control this origami-like folding process by varying the thickness and relative consistency of the silicone material adjacent to the channels across different layers or by laser-cutting at different distances from the channels. During pressurization, the channels then function as actuators that induce a permanent structural change,” said first and corresponding author Tommaso Ranzani, Ph.D., who started the study as a postdoctoral fellow in Wood’s group and now also is assistant professor at Boston University.
 
The remaining set of integrated microfluidic channels were used as additional actuators to colorize the eyes and simulate the abdominal color patterns of the peacock spider species by flowing colored fluids; and to induce walking-like movements in the leg structures. “This first MORPH system was fabricated in a single, monolithic process that can be performed in few days and easily iterated in design optimization efforts,” said Ranzani.
 
“The MORPH approach could open up the field of soft robotics to researchers who are more focused on medical applications where the smaller sizes and flexibility of these robots could enable an entirely new approach to endoscopy and microsurgery,” said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children’s Hospital, as well as Professor of Bioengineering at SEAS.
 
Additional authors on the study are Nicholas Bartlett, a Graduate Student on Wood’s team and Michael Wehner, Ph.D., a former Postdoctoral Fellow with Wood, who know is Assistant Professor at University of California Santa Cruz. The study was funded by Harvard’s Wyss Institute, the Defense Advanced Research Project Agency (DARPA), and a National Defense Science and Engineering Graduate Fellowship.