BioInteractions, a UK-based biomaterial technology company, is rolling out its new AstutePlus surface active therapeutic coating for medical devices at Compamed 2024. The company will be at the trade fair from November 11-14 showcasing AstutePlus, along with its other coating solutions.

AstutePlus is an antithrombogenic designed to prevent fibrin sheath and thrombus formation in devices that contact blood. These issues present a challenge for clinicians using central venous catheters (CVCs) because they affect the safety and effectiveness of treatments like hemodialysis.

Biointeractions said by preventing sheath formation, the AstutePlus coating lowers risk of device malfunction and other complications from frequent catheter adjustments.

“Fibrin sheath formation is a major issue for patients. It often requires invasive procedures, including catheter replacement and sheath disruption or snaring,” says Brian Rifkin, MD, of Hattiesburg Clinic. “These interventions can be uncomfortable and time-consuming for patients and may only temporarily solve the issue. There is a real need for solutions that prevent sheath formation, since there are currently no effective prophylactic therapies,” he adds.

“AstutePlus addresses fibrin sheath formation by preventing it from happening in the first place,” added Arjun Luthra, Commercial Director of BioInteractions. “AstutePlus Advanced Antithrombogenic is a Surface Active Therapeutic that combines both active and passive components to provide a multi-faceted solution. The active agents block the blood cascade mechanism therefore deactivating platelets which reduces thrombus formation and prevents fibrin sheath formation. The passive elements hinder deposition and adhesion of blood components and proteins on the device surface. This combination results in an implant that is actively shielded and protected for the lifetime of the patient, therefore providing clinicians more time to focus on caring for their patients.”

Arjun Luthra and the BioInteractions team will be at Compamed Hall 8b/N20.