Pulse Biosciences, CardioNXT Partner on First-in-Human Afib Study

Pulse Biosciences Inc. is joining forces with CardioNXT to support a planned nsPFA cardiac catheter first-in-human study focused on atrial fibrillation treatment.
 
“We are excited to announce this collaboration and the progress we’ve made integrating our circumferential nsPFA catheter with the CardioNXT iMap System,” Pulse Biosciences CEO Kevin Danahy said. “The CardioNXT navigation and mapping system was our top choice for integration with our novel nsPFA cardiac circumferential catheter. Their iMap system offers dynamic referencing to provide superior accuracy and stability when navigating our catheter to targeted tissue areas. We’re on track to initiate our first-in-human study in the first half of next year and believe this combination has the potential to achieve best-in-class clinical outcomes.”
 
The collaboration will include full integration of Pulse Biosciences’ nsPFA circumferential cardiac catheter and CardioNXT’s iMap Navigation and Mapping System, enabling electrophysiologists to successfully visualize individual cardiac structures and place the nsPFA catheter for circumferential ablations of targeted pulmonary veins in the treatment of atrial fibrillation.
 
“We are excited to partner with Pulse Biosciences to advance our shared mission of improving cardiac therapy while further demonstrating the versatility of iMap. Pulse’s nsPFA technology provides a highly differentiated catheter-based solution and the integration with our system has the potential to provide fast, accurate, effective, and safe zero-fluoro ablation of cardiac tissue for the treatment of AF,” CardioNXT CEO Jerome Edwards stated.
 
Pulse Biosciences is a bioelectric medicine company whose proprietary Nanosecond Pulsed Field Ablation (nsPFA) technology delivers nanosecond pulses of electrical energy to non-thermally clear cells while sparing adjacent noncellular tissue. The company is actively pursuing the development of its nsPFA technology for use in treating atrial fibrillation and in a select few other markets. Pulse Biosciences, CellFX, Nano-Pulse Stimulation, NPS, nsPFA and the stylized logos are among the trademarks and/or registered trademarks of Pulse Biosciences Inc. in the United States and other countries.
 
CardioNXT has developed a commercially available 3D Mapping & Navigation System that leverages internal navigation referencing with electromagnetic tracking and AI enabled complex mapping algorithms. The CardioNXT Team creates 3D Navigation & Mapping products such as the Medtronic-StealthStation, Medtronic-LocaLisa, and Olympus-Veran Systems, which have enjoyed market leadership positions in multiple clinical applications.