Mount Sinai Establishes Center for AI-Driven Pediatric Healthcare

The Icahn School of Medicine at Mount Sinai has launched the Center for Artificial Intelligence (AI) in Children’s Health, the first dedicated center of its kind in New York City—an initiative that aims to improve pediatric healthcare outcomes through artificial intelligence (AI).

The Center will develop AI-powered solutions to enhance diagnostics, personalize treatments, and optimize healthcare delivery for youths and adolescents. Benjamin S. Glicksberg, Ph.D., an expert in digital health and clinical informatics, will lead the Center.  

“The Center for AI in Children’s Health underscores Mount Sinai’s commitment to pioneering AI-driven technologies that will enable Mount Sinai to deliver world-class care to our children,” said Brendan G. Carr, M.D., CEO and professor, and Kenneth L. Davis, M.D., distinguished chair, Mount Sinai Health System. “As one of the first centers of its kind in New York City and nationwide, this unique and groundbreaking initiative positions Mount Sinai at the forefront of innovation in healthcare. Our kids are our future, and under Dr. Glicksberg’s leadership, the Center for AI in Children’s Health will advance children’s health outcomes for generations to come.” 

The Center will focus on: 

• Building an AI-driven Children’s Health Data Hub to unify multi-modal and multi-omic patient data. 
• Spearheading clinical trials for AI approaches to enhance diagnostics, predictive modeling, and real-time monitoring at Mount Sinai Kravis Children’s Hospital. 
• Advancing personalized medicine through multi-omics research, rare disease identification, and pharmacogenomics. 
• Optimizing health care delivery with Mount Sinai’s Center for Child Health Services Research to leverage AI for improving efficiency, patient outcomes, and resource allocation. 

“The establishment of the Center for Artificial Intelligence in Children’s Health exemplifies Mount Sinai’s dedication to integrating cutting-edge technologies into patient care. By harnessing the power of AI, we are offering more precise diagnostics and personalized treatments for our youngest patients,” stated Dennis S. Charney, M.D., Anne and Joel Ehrenkranz Dean at the Icahn School of Medicine at Mount Sinai and president for Academic Affairs of the Mount Sinai Health System. “With Dr. Glicksberg at the helm, this new center will be instrumental in shaping the future of pediatric medicine as we take bold steps toward innovation and excellence in health care for the next generation.” 

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Dr. Glicksberg joins Mount Sinai with significant academic and industry experience. He previously was assistant professor of Genetics and Genomic Sciences and a member of the Hasso Plattner Institute for Digital Health at Mount Sinai. He then served on the leadership team at a genomics-based drug discovery startup targeting progressive diseases of aging. His experience bridging the gap between research and clinical care—including expertise in AI-driven research, healthcare, biotechnology, and translational science—positions him as a leader in AI innovation. 

“While AI has advanced at a remarkable pace in many areas of medicine, pediatric medicine has unfortunately lagged due to stricter privacy considerations, more complicated regulatory pathways, and limited data infrastructure,” noted Dr. Glicksberg, who will also serve as associate professor of Artificial Intelligence and Human Health at the Icahn School of Medicine at Mount Sinai. “This new Center is dedicated to addressing these challenges by safely developing, testing, and embedding AI directly into child healthcare—enabling earlier diagnoses, preventive measures, computer-augmented imaging for complex conditions, expedited drug discovery, and highly personalized treatment plans. There’s no better place for this effort than Mount Sinai, or a more talented team of researchers to innovate alongside. I’m thrilled to lead this critical work and confident that we’re shaping a brighter future for child healthcare.” 

AI continues to transform healthcare, however innovation remains significantly underrepresented in child health due to specific standards necessary, but complex regulatory challenges and limited resources, delaying the benefits these technologies could bring to child health care. The Center hopes to address the current limitations by creating an integrated data infrastructure, advancing multimodal AI research, embracing personalized medicine, and enhancing health economics and care delivery. 

The Center for Artificial Intelligence in Children’s Health is established under The Mindich Child Health and Development Institute, directed by Bruce D. Gelb, M.D., and co-sponsored by the Windreich Department of Artificial Intelligence and Human Health at Mount Sinai, chaired by Girish N. Nadkarni, M.D.  

“As Chair of the Windreich Department of AI and Human Health, I’m proud to co-sponsor the Center for AI in Children’s Health,” Dr. Nadkarni said. “By harnessing the power of advanced data science and clinical expertise, we aim to usher in a new era for child healthcare—delivering faster diagnoses, personalized treatments, and transformative outcomes. Under Dr. Glicksberg’s leadership, we stand poised to shape a healthier future for children everywhere.”

The Mindich Child Health and Development Institute is a translational research enterprise striving to advance knowledge and therapies for diseases affecting infants, children, and adolescents. The Institute assembles physician-scientists and scientists in an intellectually rich and supportive environment, which fosters collaborative scientific investigation as well as training the next generation of scientific leaders for pediatric medicine. There currently are more than 100 faculty members who specialize in allergy and asthma, cardiovascular disease, neurodevelopmental disorders, obesity and diabetes, child health services, and more. 

Faculty at the Institute work in a multidisciplinary manner with researchers and physicians in departments and institutes at Mount Sinai. The Institute develops paradigms for understanding the effects of genetics and the environment on the health of infants, children, and adolescents, and personalizing pediatric medicine through genetics and genomics.

Mount Sinai’s Windreich Department of AI and Human Health is the first of its kind at a U.S. medical school, pioneering transformative advancements at the intersection of artificial intelligence and human health. The department is committed to leveraging AI in a responsible, effective, equitable, and safe manner to transform research, clinical care, education, and operations. By bringing together AI expertise, cutting-edge infrastructure, and unparalleled computational power, the department is advancing breakthroughs in multi-scale, multimodal data integration while streamlining pathways for rapid testing and translation into practice. 

The department benefits from dynamic collaborations across Mount Sinai, including with the Hasso Plattner Institute for Digital Health at Mount Sinai—a partnership between the Hasso Plattner Institute for Digital Engineering in Potsdam, Germany, and the Mount Sinai Health System—which complements its mission by advancing data-driven approaches to improve patient care and health outcomes. 

At the heart of this innovation is the Icahn School of Medicine at Mount Sinai, which serves as a central hub for learning and collaboration. This unique integration enables partnerships across institutes, academic departments, hospitals, and outpatient centers, driving progress in disease prevention, improving treatments for complex illnesses, and elevating quality of life on a global scale. 

At the Hasso Plattner Institute for Digital Health at Mount Sinai, the tools of data science, biomedical and digital engineering, and medical expertise are used to improve and extend lives. The Institute represents a collaboration between the Hasso Plattner Institute for Digital Engineering in Potsdam, Germany, and the Mount Sinai Health System. 

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with 48,000 employees working across seven hospitals, more than 400 outpatient practices, more than 600 research and clinical labs, a school of nursing, and a school of medicine and graduate education. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive healthcare solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics. The Health System includes approximately 9,000 primary and specialty care physicians and 11 free-standing joint-venture centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida.