Healthtech Startup Raises £5.75 million in Pre-Seed Funding

Clinician-led healthtech innovator Definition Health has secured £5.75 million ($7.5 million) in pre-seed funding for surgical care with cutting-edge predictive artificial intelligence (AI). The money will further fuel the enhancement of the company’s platform, designed to seamlessly integrate into healthcare systems, transforming surgical workflows.

By delivering personalized, data-driven care, Definition Health’s platform improves surgical efficiency, reduces complications, and optimizes outcomes for patients, hospitals, and insurers.

“Medicine does not stand still, nor should it. In my opinion, Definition Health is quite literally a glimpse into the future,” said orthopedic surgeon and Definition Health angel investor Dr. David Redfern, CEO of David Redfern Surgery. “Not only do Definition Health systems already improve patient safety in the hospital environment but they offer perhaps one of the Holy Grails of medicine—the opportunity to tailor treatments to specific patient attributes. To link a whole host of parameters to outcomes and understand how to improve those outcomes.”

Co-founded by Dr. Sandeep Chauhan, an internationally renowned practicing orthopedic surgeon with over two decades of clinical experience, and Dr. Rosie Scott, an NHS Clinical Entrepreneur and celebrated radiologist, Definition Health was born from a vision to modernize surgical care by addressing the inefficiencies that burden both clinicians and patients. “We saw firsthand how fragmented the surgical care process was, leading to delays, cancellations, and complications,” Dr. Chauhan stated. “Our platform streamlines the entire surgical journey, surfacing actionable patient data to clinicians, enabling them to intervene earlier and make more informed decisions, resulting in better outcomes for patients.”

U.S. hospitals face increasing pressure to maximize revenue from elective surgeries, a critical income stream that accounts for 48% of hospital gross revenue. With 40% of U.S. hospitals operating at a loss, current solutions are failing to address both financial and clinical inefficiencies. Definition Health combats this by drawing on proprietary data from more than 400,000 surgeries to build predictive models that optimize care and mitigate surgical risk. With U.S. healthcare under pressure from staffing shortages, rising costs, and growing surgical demands, Definition Health’s platform integrates predictive analytics and machine learning into clinical workflows to optimize pre-op planning, reduce complications, and accelerate recovery.

The United Kingdom-based company’s platform has already saved the NHS the equivalent of $2.6 million per 40,000 patients by reducing surgical cancellations, and Definition Health is eager to replicate this success in the United States, where outpatient surgeries are growing exponentially. As a participant in the U.K.-Florida Life Sciences Trade Corridor, the company is well-positioned to connect with key players in Florida’s healthcare market, including leading hospitals and healthcare systems, making it an ideal partner for U.S. institutions looking to improve efficiency and patient outcomes.

“As a former NHS Hospital CEO with over two decades of experience, I immediately recognised the transformative potential of Definition Health. Sandeep and Rosie’s vision for revolutionizing end-to-end surgical pathways is not just innovative, it’s essential for the future of healthcare,” stated Dame Jackie Daniel, former CEO of NHS Newcastle Hospitals, healthcare advisor to Definition Health, and a global luminary for Accenture. “Their solution is a game-changer, offering tangible benefits for both patients and front-line staff. The evaluation results are not just impressive; they’re indicative of a significant leap forward in healthcare delivery. I am truly excited to see the contribution Definition Health will make to healthcare, not only in the U.K. and U.S. but on a global scale. This is the kind of innovation that investors and healthcare systems should be paying close attention to.”

As Definition Health scales, the company is focused on expanding into key U.S. markets, starting with Florida, where the demand for surgical innovation is growing rapidly. With the success of its pre-seed round, Definition Health has opened a Series A funding round to support this growth and foster strategic partnerships in the United States. By combining AI-powered predictive analytics with seamless clinical integration, Definition Health is transforming surgical care and providing a comprehensive solution to the challenges facing hospitals globally. The company’s success in the NHS, the largest single-payer system in the world, demonstrates its capacity to deliver value-based care at scale.

Definition Health is transforming surgical care through advanced predictive AI technology. By streamlining the entire surgical journey, from pre-op to recovery, its AI-powered platform improves patient outcomes, enhances clinical workflows, and reduces costs for hospitals and insurers.