FDA Clears Prana Surgical’s Electrosurgical Device

Prana Surgical has received U.S. Food and Drug Administration (FDA) clearance for an electrosurgical device (the Prana System) that removes tissue and controls bleeding.

The Prana System is a sterile, single-use electrosurgical tool designed for use with standard generators, enabling physicians to localize and excise tissue in a controlled, minimally invasive manner.

“Receiving FDA clearance for the Prana System represents a defining milestone for our company,” Prana Surgical Co-Founder/CEO Joanna Nathan said. “Surgeons today are increasingly focused on achieving precise outcomes while minimizing disruption to healthy tissue. The Prana System was designed to support that shift by integrating targeting and excision into a single, streamlined tool.”

Minimally invasive surgery continues to evolve toward approaches that prioritize precision, efficiency, and tissue preservation. However, many procedures still require multiple instruments or tradeoffs between access, control, and tissue conservation. The Prana System is designed to address these challenges by combining localizing and cutting capabilities within a bipolar electrosurgical platform, enabling controlled tissue removal, according to the company.

“Electrosurgery is foundational to modern surgery, but there is still opportunity to improve how energy-based tools are applied in minimally invasive settings,” Nathan added. “Our goal is to introduce a new class of image-guided surgical tools that enable more precise intervention across a range of procedures.”

Following FDA clearance, Prana Surgical will initiate a controlled U.S. clinical introduction as part of its broader clinical and commercialization strategy.

The Prana System is an image-guided electrosurgical platform designed to enable minimally invasive approaches across procedures requiring precise targeting and tissue excision and conservation. The system integrates CT-guided targeting and excision into a single device to support tissue removal.

Prana Surgical is a Houston-based team of surgeons, engineers, and entrepreneurs developing image-guided surgical technologies to advance early intervention and improve treatment options for patients with various conditions, such as lung cancer. The company’s mission is to redefine early lung-cancer intervention by enabling tissue-sparing, minimally invasive surgery that prioritizes patient quality of life.