908 Devices Launches the First At-Line Spent Cell Media Analyzer for Bioprocess Labs

908 Devices, a pioneer of analytical devices for chemical and biomolecular analysis, has launched its new bioprocess analyzer, the Rebel. This first-of-its-kind, miniature CE-MS-based analyzer lets biopharma researchers accelerate process development cycles and maximize their bioreactor utilization by running media analysis at-line, anytime.
 
Biotherapeutics are produced by live cells that require cell culture media to develop properly. Their growth is dynamic and needs to be monitored regularly. Media analysis is routinely performed by a core lab or 3rd-party service provider, but the typical two-to-three week turnaround time prevents any real-time decision making by bioprocess engineers. The Rebel puts control in the bioprocess researcher’s hands. Its small, self-contained footprint fits alongside bioreactors in process development and cell culture labs. Samples can be run at-line in less than seven minutes, completely eliminating the core lab wait time. It takes calibration and data analysis off the scientists’ plate completely, providing quantitative identification and analysis on a panel of >30 analytes including all the key amino acids, biogenic amines, water soluble vitamins and dipeptides. The Rebel is built for cGLP/cGMP environments, integrating reporting, automated performance qualification and 21 CFR Part 11-compliant software. 
 
“We’re focused on building disruptive products that enable customers to make critical decisions when and where they need to,” said Dr. Kevin J. Knopp, CEO and Co-founder of 908 Devices. “The Rebel does just that by equipping biopharma PD labs, or pretty much anyone who cultures cells and uses cell media, with immediate answers. It provides a solution for the common struggle all early-stage biopharma candidate programs experience, and helps them bring promising therapeutics to market faster.” 
 
908 Devices makes point-of-need-devices ranging from rugged, handheld chemical detection tools to compact, tiny footprint analyzers and fast separation devices. These purpose-built devices provide users with the power to redefine their workflows by getting actionable answers at the point of need. The company’s devices are being used for critical applications across the globe in the life sciences and field forensic markets. 908 Devices is headquartered in the heart of Boston where it researches, designs, and manufactures products based on high-pressure mass spectrometry (HPMS) and microfluidic separation technology.