CorWave Completes Preclinical Study on its Cardiac Pump

CorWave, a French medical device company committed to the fight against heart failure, has successfully completed the first 90-day preclinical study to evaluate its left ventricular assist device (LVAD) operating synchronously with the native heart without the use of sensors. 
 
The results of the 90-day in vivo study confirm the ability of the CorWave pump to provide chronic circulatory support with exceptional hemocompatibility. Throughout the study, the device provided pulsatile blood flow, synchronized with the native heart, without the use of sensors. This pulsatile operation is intended to reduce the complications associated with current devices which produce constant blood flow, resulting in patients not having a pulse.
 
Carl Botterbusch, chief technology officer of CorWave, commented, “I am extremely proud of our entire team for their tireless work leading to this demonstration of the unique capabilities of our technology. We now have key data on durability, hemocompatibilty and the robustness of our pulsatility algorithm that will allow us to finalize the design and move into the final series of testing required to begin a clinical study.”
 
“This conclusive 90-day trial is very good news as it brings us one step closer to the transition to humans. Encouraged by this latest study, step by step we continue our work, driven by the prospect of bringing our innovative solution to heart failure patients,” added Louis de Lillers, CEO of CorWave.
 
Further work will allow CorWave to complete the development of its heart pump and start production for clinical trials.
 
CorWave develops cardiac assistance devices. CorWave’s wave membrane is a breakthrough technology that differs from today’s commercially available left ventricular assist devices (LVADs) by its physiological operation, including the ability to mimic a pulse and blood flow rates similar to those of a healthy heart. Ultimately, CorWave’s membrane pump technology is expected to reduce the complications associated with current devices and improve the management of heart failure patients. CorWave was founded in 2012 by start-up studio MD Start and is funded by renowned investors including Bpifrance, EIC Fund, Financière Arbevel, M&L Healthcare, Novo Holdings, Seventure, Sofinnova Partners and Ysios. The company has secured 80 million euros in equity and non-dilutive financing and employs more than 50 people.
 
This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 954151. CorWave’s R&D program is supported by the French State through the “Programme d’Investissements d’Avenir” (PIA). CorWave’s industrialization program is supported by the Paris Region through the call for projects “Relance Industrie”.