05.14.14
Startup firm AdvaStim Inc., a developer of advanced technology platforms for neuromodulation therapies, has entered the research and development market with a new hardware/software solution for neuromodulation therapy developers.
“Our implantable pulse generator (IPG) technology was designed to accommodate a variety of existing and emerging clinical indications. It offers developers complete independent control over waveform current, duration, rate and phase characteristics. The system architecture is modular, providing a building-block approach for easy customization,” said Laurence Derose, founder of the Beverly, Mass.-based firm.
AdvaStim’s pulse generator technology is based on the company’s VLSI-based ASICore chip architecture, along with its ASIControl embedded software. The combination, according to the company, allows for a broad range of stimulation algorithms that can deliver variable penetration of charge to a volume of neural tissue.
AdvaStim’s ASICore chip architecture is designed for multi-channel switching, user-defined output energy algorithms and external sensor data. Its compact form factor can help enable a new generation of smaller, more flexible and customizable IPGs. ASIControl embedded software is intended to give therapy developers an enhanced range of output energy parameters. It controls modulation of current amplitude and pulse duration, and allows for multi-channel delivery of simultaneous, sequential or independent pulse rates.
The company’s system architecture provides a building-block approach for customization for a number of clinical indications including:
One of the company’s collaborative partners is Cirtec Medical Systems, which provides outsourced design, development and manufacturing services for the medical device industry. The company specializes in active and passive implantable devices as well as minimally invasive surgical, diagnostic and delivery systems.
“Our implantable pulse generator (IPG) technology was designed to accommodate a variety of existing and emerging clinical indications. It offers developers complete independent control over waveform current, duration, rate and phase characteristics. The system architecture is modular, providing a building-block approach for easy customization,” said Laurence Derose, founder of the Beverly, Mass.-based firm.
AdvaStim’s pulse generator technology is based on the company’s VLSI-based ASICore chip architecture, along with its ASIControl embedded software. The combination, according to the company, allows for a broad range of stimulation algorithms that can deliver variable penetration of charge to a volume of neural tissue.
AdvaStim’s ASICore chip architecture is designed for multi-channel switching, user-defined output energy algorithms and external sensor data. Its compact form factor can help enable a new generation of smaller, more flexible and customizable IPGs. ASIControl embedded software is intended to give therapy developers an enhanced range of output energy parameters. It controls modulation of current amplitude and pulse duration, and allows for multi-channel delivery of simultaneous, sequential or independent pulse rates.
The company’s system architecture provides a building-block approach for customization for a number of clinical indications including:
- Spinal cord stimulation for chronic intractable pain;
- Deep brain stimulation for Parkinson’s disease and essential tremor;
- Vagal nerve stimulation for epilepsy and depression;
- Sacral nerve stimulation for incontinence; and
- Gastric electrical stimulation for gastroparesis and digestive-related problems.
One of the company’s collaborative partners is Cirtec Medical Systems, which provides outsourced design, development and manufacturing services for the medical device industry. The company specializes in active and passive implantable devices as well as minimally invasive surgical, diagnostic and delivery systems.