Avantor is exhibiting at Compamed 2017, November 13-16 in Düsseldorf, Germany, where the company will highlight its advanced NuSil brand in-situ cure liquid silicone rubber technology and provide information on bio-compatible lubricious silicone lubricants.
 
Technology experts are in Hall 8A, Booth L15 to discuss the company’s full range of ultra-high-purity biomaterials for use in life sciences applications, including medical implants, general healthcare and drug delivery.
 
“Our global team looks forward to sharing our latest advances with medical device manufacturers from across the industry,” said Corey Walker, executive vice president, Biomaterials and Advanced Technologies. “For more than 35 years, NuSil has been supplying medical grade silicones. As a global leader in medical grade silicones, we have been setting quality, purity and care standards to create the industry’s purest silicone materials for use in medical devices.”
 
In-Situ Cure of Liquid Silicone Rubbers
Medical grade liquid silicone rubbers (LSRs) are widely used for a broad range of implantable medical devices, including cardiovascular, neurological, urological, ophthalmic and aesthetic applications. Typically, LSRs are used to fabricate cured devices outside the body, and then the device is implanted via surgery.
 
NuSil has introduced a new innovation: A gas sterilizable dispensing system that can be prefilled with specific uncured LSRs. This new system makes it possible for medical device manufacturers to create devices that can be cured in-situ (in the body), rather than cured outside the body and implanted.
 
Designed specifically to allow gas sterilization of the uncured medical grade LSR, the new packaging solution for in-situ curable LSRs features a double-cartridge prefilled dispensing system. Each cartridge in the dispenser has a gas-permeable plunger seal, permitting an ethylene oxide sterilant gas to permeate through the plunger seal to sterilize the contents of the barrels as well as the entire system assembly.
 
Key features of the packaging system include:
 

• Disposable syringes available in multiple sizes—5, 10, 25, 50 and 75 ml
• Engineered for use in complete surgical kits
• Allows one-step sterilization of LSR components and packaging

 
The company is planning to work with medical device and surgical kit manufacturers to fully explore the potential applications of this new LSR sterilizable delivery solution, to provide a safe and beneficial new way to implement in-situ cure of silicone-based implants.
 
Lubricious Silicones for Medical Device Lubrication
NuSil silicone technology experts are available to discuss applications of the company’s advanced line of lubricious silicones for use with medical devices.
 
Medical devices can benefit from high-performance, bio-compatible lubricious silicone lubricants that reduce friction between device components and human tissue. Other desirable properties of lubricious silicone for medical devices include oxidative resistance, chemical inertness, and hydrophobicity.
 
NuSil lubricious silicones for medical device lubrication are available in a broad portfolio of off-the-shelf solutions for dispersions, fluids and greases, and self-lubricating elastomers. In addition, NuSil applications experts can work with medical instrument and device manufacturers to customize the company’s lubricious silicones to meet desired coefficient of friction (COF) and volatility levels for lubricants, curable coatings and self-lubricating elastomers.