• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    Spectrum Solutions Collaborates with UCLA School of Dentistry

    Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization

    Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty

    Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

    FDA Clears 3D Acellular Dermal Matrix
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Fixing Face Mask Form and Function

    The Heart of the Matter: Trends in Cardiology

    Virtually the Same? The Challenges of Online Conferences

    Digital Health Delivers During a Year for the Ages

    Advanced Technology for Staking and Swaging Medical Plastics
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    PTI Engineered Plastics Inc.

    Spectrum Plastics Group

    FUTEK Advanced Sensor Technology Inc.

    Concise Engineering

    Medicoil
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Meeting Critical Ventilator Product Requirements Amid Pandemic

    Impact of COVID-19 on the Medtech Supply Chain

    Finding the Upside to a Challenging Year

    Preparing Your Design Controls for FDA Approval

    A 'Trial and Error' Approach to Micromolded Parts
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Unicep

    Medbio LLC

    Element

    MW Life Sciences

    K-Tube Technologies
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    Robot-Assisted Throat Cancer Surgery Gets Assist from Novel Optical Device

    UC Davis technology brings augmented reality to the operating room.

    Robot-Assisted Throat Cancer Surgery Gets Assist from Novel Optical Device
    Laura Marcu, a professor in the UC Davis Department of Biomedical Engineering who developed the technology, and D. Gregory Farwell, professor and chair of the UC Davis Department of Otolaryngology. Image courtesy of UC Davis Health.
    Related CONTENT
    • Diagnostic May Bring Faster, Cheaper Cancer Testing to Remote Settings
    • Application Detects Cancer Cells in Abdominal Cavity in Real Time
    • New AI 'Smart Pill' Images Gut to Spot Cancer
    • Blood Test May Help Doctors Catch Pancreatic Cancer Early
    • FDA Grants Lucid Diagnostics Breakthrough Device Designation for Esophageal DNA Test
    UC Davis Health02.11.19
    For hard-to-reach tumors at the back of the throat, robots can assist surgeons to remove cancers in a less invasive way. But this high-tech approach has a drawback: the surgeon’s inability to assess through touch whether they’ve been able to get all of the cancer out.
     
    An innovative new device developed at UC Davis is helping to change that. Based on fluorescence lifetime imaging microscopy (FLIm), the device can be used in tandem with robotic surgery to distinguish between cancerous and benign tissue, guiding the physician in real time to achieve a more precise surgical outcome for the patient.
     
    In a first-in-human, proof-of-principle study published in Scientific Reports, a Nature publication, UC Davis researchers report on their ability to successfully integrate the FLIm tool with a surgical robot to allow real-time evaluation of the different tissue types in patients undergoing oral cancer surgery without using contrast agents. First studied in animal models, the technology has now been used in about 30 human patients with cancers of the tonsil and base of the tongue.
     
    “We are the first to demonstrate implementation of augmented reality in patients and in conjunction with robotic surgery,” said Laura Marcu, a professor in the UC Davis Department of Biomedical Engineering who developed the technology.
     
    FLIm is a technique that measures the autofluorescence properties of certain molecules in tissue in the form of wavelength (or color) and lifetime (or the time a molecule emits light). Since tumor tissue is made up of molecules different from those in normal tissue, tumors also have different fluorescence properties. This allows the autofluorescence to encode diagnostic information to help the surgeon as he removes tissue.
     
    “The FLIm features are augmented instantaneously in the surgeon’s field of view so the surgeon can see tissue properties that cannot be seen otherwise,” Marcu said.
     
    New Optical Device Takes Science from Bench To Bedside
    For this work Marcu teamed up with D. Gregory Farwell, professor and chair of the UC Davis Department of Otolaryngology – Head and Neck Surgery, to use the device to help guide him during complex oral cancer surgeries. When Farwell began using the robot to do complex head and neck surgeries, the two figured out a way to incorporate the device with the robot’s technology.
     
    “It’s a special application for patients with a tumor at the back of their throat,” Farwell said. “These tumors are very difficult to access, and they traditionally required extensive surgery that involved cutting the jaw and reconstructing the jaw to allow us to get back there. In selected patients, we can use the robot to gain access to tumors that historically we could not get to less invasively.”
     
    He added that head and neck cancers are on the rise because of the spread of human papillomavirus, which can lead to cancer even in people without traditional risk factors such as excessive drinking and smoking.
     
    “We have seen patients in their 30s and 40s, but it is showing up increasingly in middle-aged men,” he said. “And it is dramatically increasing in incidence.”
     
    Cancers of the head and neck can be very challenging to treat because there is little margin for error, Marcu added.
     
    “In the head and neck, where tumors are present in functional areas, you don’t want to cut too much,” she said. “You want to preserve functional tissue, but remove the entire tumor. This where this tool optimizes the procedure and provides the surgeon with additional information.”
     
    Specially Designed Optics Augment Surgeon’s Precision Tumor Removal
    FLIm uses light to excite molecules in tissue and measure how long they emit light of their own after they are excited. Different types of molecules emit light at different rates. FLIm can measure the rates, and that information is used to distinguish between different types of tissue. The device employs fiber optics to deliver and collect the light.
     
    Marcu and Farwell found a way to insert the fiber optic device through a robotic port to assess the tissue, remove it and then replace it with a standard surgical instrument. Sitting at a robotic console, the surgeon can then use the instantaneous findings from the device to remove additional tissue, as needed.
     
    Marcu explained that the information gathered by the device is more detailed than what can be gleaned from a microscopic analysis of a small tissue sample taken during surgery because it generates diagnostic information based on the intrinsic molecular contrast between normal tissue and cancer tissue. She said it may even be able to help find early cancer growth not detected using regular pathology.
     
    “Pathology sees things in black and white,” she said. “There is a grey area where you don’t know if it is cancer or not cancer,” she said. “You can do the genomic analysis and other tests that can provide additional information, but it’s not done in real time and would take weeks. With this device, the surgeon may be able to cut out more tumor or preserve more normal tissue than what had been anticipated because of the information the device can provide in the operating room.”
     
    For the next phase of their work, Marcu and Farwell are recruiting up to 80 more patients to further develop and refine the technique. Marcu also plans to team with urological surgeons to use the device for prostate cancer patients.
     
    In addition to Marcu and Farwell, UC Davis authors included: D. Gorpas, J. Phipps, J. Bec, D. Ma, D. Yankelevich, R. Gandour Edwards and A. Bewley. This study was conducted in collaboration with Intuitive Surgical Inc. in Sunnyvale, Calif.
    Related Searches
    • scientific reports
    • surgical
    • cancer surgery
    • tumor
    Related Knowledge Center
    • Surgical
    Suggested For You
    Diagnostic May Bring Faster, Cheaper Cancer Testing to Remote Settings Diagnostic May Bring Faster, Cheaper Cancer Testing to Remote Settings
    Application Detects Cancer Cells in Abdominal Cavity in Real Time Application Detects Cancer Cells in Abdominal Cavity in Real Time
    New AI New AI 'Smart Pill' Images Gut to Spot Cancer
    Blood Test May Help Doctors Catch Pancreatic Cancer Early Blood Test May Help Doctors Catch Pancreatic Cancer Early
    FDA Grants Lucid Diagnostics Breakthrough Device Designation for Esophageal DNA Test FDA Grants Lucid Diagnostics Breakthrough Device Designation for Esophageal DNA Test
    Smartphone Use Risks Eye Examination Misdiagnosis Smartphone Use Risks Eye Examination Misdiagnosis
    FDA Clears United Imaging Healthcare FDA Clears United Imaging Healthcare's uEXPLORER Total-Body Scanner
    FDA OKs TransEnterix FDA OKs TransEnterix's Senhance Ultrasonic System
    Largest Medical AI Imaging Technology Platform Adds Capabilities to Speed Radiology Reports Largest Medical AI Imaging Technology Platform Adds Capabilities to Speed Radiology Reports
    Titan Medical Gains Seven Patents for Single-Port Robotic Surgery Titan Medical Gains Seven Patents for Single-Port Robotic Surgery
    3D Printed Ingestible Capsule Can Be Wirelessly Controlled 3D Printed Ingestible Capsule Can Be Wirelessly Controlled
    CMR Surgical Launches First U.S. Training Program for Versius CMR Surgical Launches First U.S. Training Program for Versius
    Flexible Electrodes Can Peer into the Secret Life of Brain Cells Flexible Electrodes Can Peer into the Secret Life of Brain Cells
     Phillips-Medisize Partners With InterSystems in Connected Health Platform Phillips-Medisize Partners With InterSystems in Connected Health Platform
    The Top 10 Medical Innovations for 2019 The Top 10 Medical Innovations for 2019

    Related Breaking News

    • Cardiovascular | Surgical
      Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

      Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots

      UBC Okanagan research could transform the current gold standard for heart valves.
      Sam Brusco, Associate Editor 01.27.21

    • Cardiovascular | Surgical
      Haemonetics to Acquire Cardiva for Up to $510M

      Haemonetics to Acquire Cardiva for Up to $510M

      Enhances penetration into the large and growing interventional cardiology and electrophysiology markets.
      PR Newswire 01.20.21

    • Cardiovascular | Surgical
      Abbott Wins Expanded Medicare Coverage for MitraClip

      Abbott Wins Expanded Medicare Coverage for MitraClip

      Includes patients with secondary (or functional) mitral regurgitation resulting from heart failure.
      Abbott Laboratories 01.20.21


    • Surgical
      Freehand Partners with Imperial Medical Solutions

      Freehand Partners with Imperial Medical Solutions

      Supports the introduction of its surgical robots in India, Sri Lanka, Malaysia and the Caribbean.
      Freehand 01.19.21

    • Surgical
      TransEnterix Wins EU Approval for Robotic Surgical Machine Vision System

      TransEnterix Wins EU Approval for Robotic Surgical Machine Vision System

      Intelligent Surgical Unit enables augmented intelligence on the Senhance surgical system.
      Business Wire 01.19.21

    • Surgical
      Moon Surgical Expands Leadership Team

      Moon Surgical Expands Leadership Team

      Adds Jeffery Alvarez, David Noonan, and Nicolas Linard.
      Moon Surgical 01.14.21


    • Neurological | Surgical
      FDA OKs ClearMind Biomedical

      FDA OKs ClearMind Biomedical's Axonpen Neuroendoscope

      Requires only a narrow channel of 6.5mm through the skull for insertion into the brain.
      PR Newswire 01.12.21

    • Packaging & Sterilization | Surgical
      Olympus Releases ScopeLocker Endoscope Storage Cabinet

      Olympus Releases ScopeLocker Endoscope Storage Cabinet

      HEPA hinged door endoscope storage system addresses infection prevention needs in busy GI suites.
      Olympus 01.06.21

    • Surgical
      FDA Clears EndoRotor to Remove Dead Pancreatic Tissue

      FDA Clears EndoRotor to Remove Dead Pancreatic Tissue

      Treats patients with necrotic tissue resulting from complications of acute pancreatitis.
      U.S. Food and Drug Administration 01.04.21


    • Cardiovascular | Neurological | Surgical
      FDA OKs Rapid Medical

      FDA OKs Rapid Medical's Steerable Neurovascular Guidewire

      Provides efficient access in difficult neuro and peripheral vascular procedures.
      Business Wire 01.04.21

    • Surgical
      Clinical Trial to Study Impact of ActivePure Technology on Surgical Site Infections

      Clinical Trial to Study Impact of ActivePure Technology on Surgical Site Infections

      The study will use 50 noncardiac, adult operating rooms at Cleveland Clinic.
      Aerus Medical 12.14.20

    • Cardiovascular | Surgical
      Foldax Earns FDA Approval for Biopolymer Mitral Heart Valve Study

      Foldax Earns FDA Approval for Biopolymer Mitral Heart Valve Study

      Valve designs intended to resist calcification, withstand stresses and strains without failure.
      Business Wire 12.14.20


    • Surgical
      Aspen Surgical Acquires Protek Medical Products

      Aspen Surgical Acquires Protek Medical Products

      Acquisition bolsters Aspen’s portfolio of patient and staff safety products.
      Business Wire 11.24.20

    • Surgical
      FDA Clears Penumbra

      FDA Clears Penumbra's Lightning 12 Aspiration Catheter for Pulmonary Embolism

      Indigo Aspiration System with Lightning 12 removes these difficult-to-access, life-threatening clots.
      Business Wire 11.20.20

    • Diagnostics | Surgical
      Allotrope Medical

      Allotrope Medical's StimSite Wins FDA Nod

      Lets surgeons use existing surgical instruments to help locate, identify ureters using electrical stimulation.
      PR Newswire 11.18.20


    Trending
    • Senseonics Forges Strategic Collaboration With Ascensia Diabetes Care
    • Portable, Home-Use Device Quickly Measures Inflammation Levels
    • Henry Schein Buys Majority Interest In Prism Medical Products
    • Top 10 Trends In The Medical Device And Equipment Industry
    • Masimo Earns CE Mark For New Fingertip Pulse Oximeter
    Breaking News
    • Spectrum Solutions Collaborates with UCLA School of Dentistry
    • Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization
    • Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty
    • Twist on Heart Valve Design Boosts Blood Flow, Prevents Clots
    • FDA Clears 3D Acellular Dermal Matrix
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Pharmaceutical Focus: A Look at Combination Products
    • The Printed World: Additive Manufacturing in Medtech
    • The Lost Year: 2020 Year in Review
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    PepsiCo and Beyond Meat Partner to Develop Plant-Based Protein
    New Study on Sage Extract Formula Suggests Memory Enhancement
    Omega-3s Evidenced to Reduce Low-Grade Inflammation in Elderly Men
    Coatings World

    Latest Breaking News From Coatings World

    Mayzo Makes 2 Appointments
    Mississippi Lime Company Announces New Director of Safety
    IFS Coatings Launches IFS Puroplaz PE20 Texture
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Spectrum Solutions Collaborates with UCLA School of Dentistry
    Kwivik Therapeutics, EirMed Partner to Accelerate Product Commercialization
    Europe Marks its First Successful Remote Robotic-Assisted Coronary Angioplasty
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Lilly, Vir, GSK Partner to Evaluate COVID Combo Therapies
    Novartis Invests in Credence MedSystems
    Ajinomoto Bio-Pharma, Humanigen Expand Manufacturing Agreement
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Coty to Shut Down Manufacturing Site in Cologne, Germany
    L’Occitane Files for Bankruptcy in U.S.
    Bésame Cosmetics Collaborates with Disney on Mary Poppins Collection
    Happi

    Latest Breaking News From Happi

    CLT Introduces Private Label Solid Air Freshener Cones
    The Florida Sunscreen Symposium Is Back!
    TFF Opens Nominations for 2021 Awards
    Ink World

    Latest Breaking News From Ink World

    Epson Partner Creates Label Applicators for Pharmaceutical Products
    Smurfit Kappa Sets New Sustainability Targets with Better Planet 2050
    Georgia-Pacific Acquires 3rd HP PageWide Corrugated Press to Expand Hummingbird Digital Printing
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Arjobex acquires MDV Group
    Fix-A-Form eyes global expansion
    McCracken Label installs Fujifilm water-wash plate system
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Nice-Pak Receives EPA Approval for Disinfecting Wipes
    Rockline to Invest $18 Million in Arkansas
    Essity’s Sales Negatively Impacted by Covid-19 Pandemic
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ChoiceSpine's Tiger Shark Cervical Spacer Earns Additional 510(k)
    FDA Green Lights Inspired Spine's Trident SI Joint Screw System
    FDA Clears Method to Extract Bone Measurements From X-Rays
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Osram Sees Jump in Profits in Preliminary 2020 Report
    LG Display Reports 4Q 2020 Results
    Xerox Releases 4Q, Full Year Results

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login