• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Opinions
    • Top 30
    • Research
    • Supply Chain
    • Device Sectors
    • Directory
    • Events
    • Resources
    • Microsites
    • More
  • Magazine
  • News
  • Opinions
  • Top 30
  • Research
  • Supply Chain
  • Device Sectors
  • Directory
  • Events
  • Resources
  • Microsites
  • Current / Back Issues
    Features
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Reprints
    Subscribe Now
    Advertise Now
    Top Features
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    OEM News
    Supplier News
    Service / Press Releases
    Online Exclusives
    Press Releases
    People in the News
    Product & Service Releases
    Supplier News
    Medtech Makers
    Technical Features
    International News
    Videos
    Product & Service Releases
    Live From Shows
    Top News
    Cretex Companies CEO Steps Down

    Data Show Porex's Medical Device Filtration Materials Protect Against Virus, Bacteria Spread

    Endoscopic Hemostasis Devices Market Valued at $730 Million

    Henry Schein Buys Majority Interest in Prism Medical Products

    Boston Scientific's Vercise Genus DBS Earns FDA Approval
    From the Editor
    Blogs
    Guest Opinions
    Top Opinions
    Pharmaceutical Focus: A Look at Combination Products

    The Printed World: Additive Manufacturing in Medtech

    The Lost Year: 2020 Year in Review

    Extrusion Evolution

    Little Big Parts: Micromolding Under the Microscope
    Top 30 Medical Device Companies
    Market Data
    White Papers
    Top Research
    Fixing Face Mask Form and Function

    The Heart of the Matter: Trends in Cardiology

    Virtually the Same? The Challenges of Online Conferences

    Digital Health Delivers During a Year for the Ages

    Advanced Technology for Staking and Swaging Medical Plastics
    3D/Additive Manufacturing
    Contract Manufacturing
    Electronics
    Machining & Laser Processing
    Materials
    Molding
    Packaging & Sterilization
    R&D & Design
    Software & IT
    Testing
    Tubing & Extrusion
    Cardiovascular
    Diagnostics
    Digital Health
    Neurological
    Patient Monitoring
    Surgical
    Orthopedics
    All Companies
    Categories
    Company Capabilities
    Add New Company
    Outsourcing Directory
    Qosina Corp.

    Medbio LLC

    Element

    PTI Engineered Plastics Inc.

    Unicep
    MPO Summit
    Industry Events
    Webinars
    Live From Show Event
    Industry Associations
    Videos
    Career Central
    eBook
    Slideshows
    Top Resources
    Meeting Critical Ventilator Product Requirements Amid Pandemic

    Impact of COVID-19 on the Medtech Supply Chain

    Finding the Upside to a Challenging Year

    Preparing Your Design Controls for FDA Approval

    A 'Trial and Error' Approach to Micromolded Parts
    Companies
    News Releases
    Product Releases
    Press Releases
    Product Spec Sheets
    Service Releases
    Case Studies
    White Papers
    Brochures
    Videos
    Outsourcing Directory
    Concise Engineering

    Medicoil

    Medbio LLC

    maxon

    Element
    • Magazine
      • Current/Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Editions
      • Subscribe Now
      • Advertise Now
    • News
    • Directory
      • All Companies
      • ALL CATEGORIES
      • Industry Associations
      • Company Capabilities
      • Add Your Company
    • Supply Chain
      • 3D/Additive Manufacturing
      • Contract Manufacturing
      • Electronics
      • Machining & Laser Processing
      • Materials
      • Molding
      • Packaging & Sterilization
      • R&D & Design
      • Software & IT
      • Testing
      • Tubing & Extrusion
    • Device Sectors
      • Cardiovascular
      • Diagnostics
      • Digital Health
      • Neurological
      • Patient Monitoring
      • Surgical
      • Orthopedics
    • Top 30 Company Report
    • Expert Insights
    • Slideshows
    • Videos
    • Podcasts
    • Resources
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • White Papers
      • Case Studies
      • Product Spec Sheets
      • Market Data
    • MPO Summit
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Microsite
      • Companies
      • Product Releases
      • Product Spec Sheets
      • Services
      • White Papers / Tech Papers
      • Press Releases
      • Videos
      • Literature / Brochures
      • Case Studies
    • About Us
      • About Us
      • Contact Us
      • Advertise with Us
      • eNewsletter Archive
      • Privacy Policy
      • Terms of Use
    Breaking News

    New Coronary CT Image Analysis Tech Flags Heart Attack Risk Years in Advance

    Caristo Diagnostics, an Oxford University spinout company, has been launched to commercialize the technology.

    New Coronary CT Image Analysis Tech Flags Heart Attack Risk Years in Advance
    Related CONTENT
    • Rubbery Bioelectronic Cardiac Patch Can Monitor, Treat Heart Disease
    • Solid Growth Expected for Global Intraoperative Monitoring Electrodes Market
    • Global Coronary Stents Market to Exceed $15.1 Billion by 2027
    • Philips Introduces Solid Core Pressure Guide Wire for Coronary Artery Interventional Procedures
    • Eko Awarded $2.7 Million Grant for Clinical Study on Valvular Heart Disease Detection
    University of Oxford10.09.18
    Every year, over 100,000 people die from a heart attack or related stroke in the UK alone, and heart disease and stroke remain the two biggest overall causes of death worldwide. Heart attacks are often caused by inflamed plaques dislodging from the coronary artery and blocking blood getting to the heart. Yet there is no method that allows for early detection of a potentially fatal build-up of plaque that could trigger a heart attack. Caristo’s technology, which has been developed as part of a research collaboration led by Oxford University academics, is based on the novel scientific discovery that the fat tissue surrounding the coronary arteries senses the presence of inflammation in the coronary artery. This change can be detected by analysis of routine coronary CT angiograms (CCTA) using Caristo’s proprietary technology, producing a new measure called the Fat Attenuation Index (FAI) which accurately quantifies the extent of inflammation in the coronary arteries supplying the heart.
     
    The FAI can be combined with other known risk factors and imaging characteristics to create a new Cardiac Risk score (CaRi), which provides a greater level of prognostic insight compared with any existing risk-assessment biomarker. With Caristo’s technology, clinicians would be able to identify early those people who are at risk of having a heart attack and take preventative steps, such as lifestyle modification and initiating preventive medication, before it strikes.
     
    Caristo’s technology is hardware agnostic and can be assessed on any standard CCTA. This includes existing CCTAs, giving clinicians the opportunity to re-evaluate a patient’s future risk of having a heart attack. By offering the technology on a SaaS basis, the technology can be deployed into hospitals without any changes to hospital infrastructure. This new technology can be used by healthcare providers and the biopharmaceutical industry, as a companion diagnostic to guide deployment of treatments in primary and secondary prevention.  
     
    The company’s launch comes shortly after a study into FAI, which is based on analysis of over 3,900 patients in both Europe and the United States and includes follow up data for up to a decade, was published in The Lancet in August. At the same time, Professor Charalambos Antoniades, inventor of the FAI technology who led the study, presented his findings at the European Society of Cardiology Congress.
     
    Caristo Diagnostics has raised £2m in seed financing, in a round backed by a consortium of investors, including Oxford Technology Investment Fund, Longwall Ventures, and Oxford Sciences Innovation. The development and launch of Caristo has been supported by Oxford University Innovation. The underpinning research into FAI was conducted collaboratively with partners including the Cleveland Clinic and the University of Erlangen and funded in part by the British Heart Foundation. The funding will be used together with a recently awarded Innovate UK grant for £1.9m, to further develop and then deploy Caristo’s underpinning technology.
     
    Professor Charalambos Antoniades, of the Oxford University Division of Cardiovascular Medicine, and founder of Caristo Diagnostics, said: “This new technology may prove transformative for primary and secondary prevention. For the first time, we have a set of biomarkers, derived from a routine test used anyway as part of everyday clinical practice, that measures what we call ‘the residual cardiovascular risk’, currently missed by all risk scores and non-invasive tests. Knowing who is at high risk for a heart attack could allow us to intervene early enough to prevent it. I expect these biomarkers to become an essential part of standard coronary CT angiography reporting in the coming years.”
     
    Dr. Victoria Sanchez, Senior Licensing and Ventures Manager at Oxford University Innovation, added: “Heart disease remains the world’s biggest killer—claiming over a hundred thousand lives every year in the UK alone. In many cases, these deaths could be avoided, yet instead are treated reactively after the damage has been done. This technology has the potential to give doctors unparalleled insight into their patients’ prognosis, and make informed treatment decisions with a greater level of confidence. Caristo turns the battle against heart disease from reactive to preventative, increasing chances of avoiding a fatal cardiac incident and saving billions in cardiac care while being relatively inexpensive for hospitals to implement.”
     
    Professor Milind Desai, staff cardiologist at the Cleveland Clinic, added: “This is an exciting new technology which has the potential for providing a simple, non-invasive answer to detect patients at risk for future fatal heart attacks. More importantly, it highlights the incredible value of cross-continent collaboration to validate the findings in different populations.”
     
    Professor Metin Avkiran, Associate Medical Director at the British Heart Foundation, which funded the research that developed FAI, added: “Most heart scans are good at spotting blockages caused by large plaques, but not the smaller, high-risk plaques that are likely to rupture and cause a heart attack. This new technique could be a game changer—allowing doctors to spot those 'ticking time bomb' patients who are most at risk of a heart attack, and getting them on to intensive treatment. This would undoubtedly save lives. By using this non-invasive scan, we could prevent a lurking heart attack that might occur down the road. But it also potentially gives us a real-time window into tracking the effect of drugs on inflamed arteries, helping us to identify new life-saving therapies.”
    Related Searches
    • non-invasive
    • detection
    • oxford
    • blood
    Related Knowledge Center
    • Digital Health
    • Software & IT
    • Cardiovascular
    Suggested For You
    Rubbery Bioelectronic Cardiac Patch Can Monitor, Treat Heart Disease Rubbery Bioelectronic Cardiac Patch Can Monitor, Treat Heart Disease
    Solid Growth Expected for Global Intraoperative Monitoring Electrodes Market Solid Growth Expected for Global Intraoperative Monitoring Electrodes Market
    Global Coronary Stents Market to Exceed $15.1 Billion by 2027 Global Coronary Stents Market to Exceed $15.1 Billion by 2027
    Philips Introduces Solid Core Pressure Guide Wire for Coronary Artery Interventional Procedures Philips Introduces Solid Core Pressure Guide Wire for Coronary Artery Interventional Procedures
    Eko Awarded $2.7 Million Grant for Clinical Study on Valvular Heart Disease Detection Eko Awarded $2.7 Million Grant for Clinical Study on Valvular Heart Disease Detection
    Shielded Stem Cells Reduce Heart Attack Damage Shielded Stem Cells Reduce Heart Attack Damage
    FDA OKs Siemens Healthineers FDA OKs Siemens Healthineers' SOMATOM On.site for Bedside CT Head Scans
    How Are MPO’s Top 30 Addressing COVID-19? How Are MPO’s Top 30 Addressing COVID-19?
    FDA Clears Siemens Healthineers FDA Clears Siemens Healthineers' Aidan AI
    PulseCam Maps Blood Flow PulseCam Maps Blood Flow
    Edwards Pauses Enrollments in Pivotal Mitral, Tricuspid Trials Edwards Pauses Enrollments in Pivotal Mitral, Tricuspid Trials
    Advanced Sterilization Products Extends the Lifespan of N95 Masks Advanced Sterilization Products Extends the Lifespan of N95 Masks
    Customized Pacemakers May Learn What Our Hearts Need Customized Pacemakers May Learn What Our Hearts Need
    Building a Safer Heart Pump Building a Safer Heart Pump
    GE Healthcare and Lantheus Announce Start of a Phase 3 Clinical Trial of Flurpiridaz GE Healthcare and Lantheus Announce Start of a Phase 3 Clinical Trial of Flurpiridaz

    Related Breaking News

    • Diagnostics
      FDA OKs Canon Medical

      FDA OKs Canon Medical's AI-Powered, 90cm Bore CT

      Company claims the Aquilion Exceed LB CT offers the industry's largest bore opening.
      Sam Brusco, Associate Editor 01.21.21

    • Cardiovascular
      First Heart Failure Patient Treated With Impulse Dynamics

      First Heart Failure Patient Treated With Impulse Dynamics' CCM Therapy in Brazil

      The Optimizer delivers cardiac contractility modulation therapy, the company’s proprietary technology, to the heart.
      Business Wire 01.21.21

    • Cardiovascular
      Boston Scientific to Acquire Preventice for Up to $925M

      Boston Scientific to Acquire Preventice for Up to $925M

      Acquisition of external cardiac monitoring technologies, services provider to expand rhythm management diagnostics portfolio.
      PR Newswire 01.21.21


    • Diagnostics
      RSIP Vision Announces Versatile Medical Image Segmentation Tool

      RSIP Vision Announces Versatile Medical Image Segmentation Tool

      Delivers efficient anatomical measurements and better treatment options.
      RSIP Visions 01.20.21

    • Cardiovascular | Surgical
      Haemonetics to Acquire Cardiva for Up to $510M

      Haemonetics to Acquire Cardiva for Up to $510M

      Enhances penetration into the large and growing interventional cardiology and electrophysiology markets.
      PR Newswire 01.20.21

    • Cardiovascular | Surgical
      Abbott Wins Expanded Medicare Coverage for MitraClip

      Abbott Wins Expanded Medicare Coverage for MitraClip

      Includes patients with secondary (or functional) mitral regurgitation resulting from heart failure.
      Abbott Laboratories 01.20.21


    • Diagnostics
      Thermo Fisher Buys Mesa Biotech for $450M

      Thermo Fisher Buys Mesa Biotech for $450M

      Mesa Biotech developed, commercialized a PCR-based rapid POC testing platform for detecting infectious diseases.
      PR Newswire 01.20.21

    • Cardiovascular | Patient Monitoring
      Hillrom to Buy Bardy Diagnostics for $375M

      Hillrom to Buy Bardy Diagnostics for $375M

      Advances digital health offering with expansion into attractive ambulatory cardiac monitoring segment.
      PR Newswire 01.19.21

    • Diagnostics
      Owlstone Medical Introduces Breath Biopsy Panel for Respiratory Diseases

      Owlstone Medical Introduces Breath Biopsy Panel for Respiratory Diseases

      Supports research to distinguish between different types of chronic inflammatory airway diseases.
      Owlstone Medical 01.19.21


    • Cardiovascular
      Occlutech

      Occlutech's Atrial Flow Regulator Earns Breakthrough Status for HF

      First-in-class, implantable Atrial Flow Regulator (AFR) for heart failure (HF) patients.
      PR Newswire 01.19.21

    • Cardiovascular | Diagnostics
      FDA OKs MRI for Impulse Dynamics

      FDA OKs MRI for Impulse Dynamics' Optimizer CCM Delivery Systems

      FDA clears potential hurdle for many heart failure patients.
      Business Wire 01.19.21

    • Digital Health | Software & IT
      Philips Buys Capsule Technologies in $635M Deal

      Philips Buys Capsule Technologies in $635M Deal

      Capsule offers vendor-neutral Medical Device Information Platform with an SaaS business model.
      GlobeNewswire 01.19.21


    • Cardiovascular
      FineHeart Successfully Tests Wireless TET System

      FineHeart Successfully Tests Wireless TET System

      A breakthrough in treating patients with severe heart failure.
      FineHeart 01.18.21

    • Cardiovascular
      U.S. TAVR Market Projected to Reach Nearly $5 Billion by 2030

      U.S. TAVR Market Projected to Reach Nearly $5 Billion by 2030

      The use of TAVR over open surgical techniques for replacing an aortic valve has exploded globally in recent years.
      GlobalData 01.15.21

    • Diagnostics
      Rapid Antigen Tests Manufacturer Acquires BIOLAB

      Rapid Antigen Tests Manufacturer Acquires BIOLAB

      Deal will create jobs and increase Innova's U.S. COVID-19 test kit manufacturing capability.
      Innova Medical Group Inc. 01.14.21


    Trending
    • Masimo Earns CE Mark For New Fingertip Pulse Oximeter
    • Portable, Home-Use Device Quickly Measures Inflammation Levels
    • Understanding Food-Grade Vs. Biocompatibility For Medical Device Materials
    • Telemedicine, Regulatory Changes To Characterize Medtech Industry In 2021
    • Medtech Matters: Surgeons Scrubbing In Virtually
    Breaking News
    • Cretex Companies CEO Steps Down
    • Data Show Porex's Medical Device Filtration Materials Protect Against Virus, Bacteria Spread
    • Endoscopic Hemostasis Devices Market Valued at $730 Million
    • Henry Schein Buys Majority Interest in Prism Medical Products
    • Boston Scientific's Vercise Genus DBS Earns FDA Approval
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Pharmaceutical Focus: A Look at Combination Products
    • The Printed World: Additive Manufacturing in Medtech
    • The Lost Year: 2020 Year in Review
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    NIH Study Compares Low-Fat, Plant-based to Low-Carb, Animal-Based Diet
    Gadot Positions Mineral Line for Vegan Market
    Nutritfy India to Launch Global Broadcast Channel Covering Nutrition
    Coatings World

    Latest Breaking News From Coatings World

    LINE-X Launches Dealer Program with International Truck
    PPG Reports Q4, Full-year 2020 Financial Results
    BASF Begins Implementing Ralignment of Global Business Services Unit
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Cretex Companies CEO Steps Down
    Data Show Porex's Medical Device Filtration Materials Protect Against Virus, Bacteria Spread
    Endoscopic Hemostasis Devices Market Valued at $730 Million
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Pfizer, BioNTech Enter Vax Pact with COVAX
    FDA Approves Janssen’s CABENUVA
    AGC Biologics Appoints Boulder Site GM
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Coty Appoints Chief Procurement Officer
    Lageen Tubes Launches Mono-Material PE Tube Solutions
    Jason Jones Loses Battle with Covid-19
    Happi

    Latest Breaking News From Happi

    Carol’s Daughter Adds New Hair Products
    Moroccan Gold Series Launches NuDo Shampoo
    Youbody Debuts Waterless Body Wash
    Ink World

    Latest Breaking News From Ink World

    BOBST Demonstrates Future of Flexible Packaging Production at Virtual Open House
    Morancé Soudure France Adds Comexi F2 MC 10-color Flexo Press
    AR Packaging Acquiring Firstan Holdings Ltd
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Gallus planning virtual event for March
    Lemu Group engineers mask-making machine
    Niagara Label upgrades with Nilpeter flexo press
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Freudenberg to Establish Apparel Interlining Competence Centers
    Minet Adds Spunlace Line in Romania
    Lemu Group Engineers Mask-Making Machine
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Cretex Companies CEO Steps Down
    Conformis Enters Development & Supply Agreement with SITES Medical
    Sectra, RSA Biomedical Sign Distribution Agreement for Implant Stability Tool
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    UDC Subsidiary Adesis' Website Wins 2020 MarCom Platinum Award
    Ambiq Wins IoT Semiconductor Company of the Year Award
    Ynvisible Names Michael Robinson CEO, Jani-Mikael Kuusisto SVP Ventures

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login