Globe Newswire08.29.17
Integra LifeSciences, a global medical technology company, has announced the publication of a new economic study, “A cost-benefit analysis of using polyethylene glycol hydrogel sealant versus fibrin glue as a dural sealant for posterior fossa surgery in the United States.” The study, published in the Journal of Health Economics and Outcomes Research, demonstrated an average cost savings of $1,666 per patient when using Integra’s DuralSeal dural sealant versus fibrin glue.
Cerebrospinal fluid (CSF) leaks after posterior fossa surgery are a significant cause of longer hospital stays, hospital readmissions and other costly post-surgical interventions. This study demonstrated that the greater clinical effectiveness of Integra’s DuraSeal dural sealant at preventing CSF leaks compared to fibrin glue after posterior fossa surgery may help hospitals reduce costs.
The study, conducted by Dr. Marissa J. Carter, a renowned health economist, biostatistician, and clinical trial designer, confirmed a positive, consistent, cost-benefit that averaged $1,666 per patient for hospitals and surgeons who choose Integra’s DuraSeal dural sealant instead of fibrin glue. The study included 200 real-world patients in the United States who underwent posterior fossa neurosurgery.
The potential savings are based on the proven clinical efficacy of DuraSeal versus fibrin glue to reduce incisional cerebrospinal fluid leaks as found by Than et. al. in their independent clinical study, “Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery,” conducted at the Johns Hopkins University School of Medicine.1
“Integra understands that today’s healthcare providers must deliver the best treatment options to patients in a cost-effective way,” said Ajit Patwardhan, M.D., senior medical director, Integra LifeSciences. “Integra’s DuraSeal brand dural sealant is the only dural sealant indicated for dural closure with both clinical and economic evidence. This evidence makes DuraSeal the better clinical choice for surgeons and patients while also meeting the cost considerations of hospital administrators and operating room directors.”
Integra’s DuraSeal dural sealant is a polyethylene glycol hydrogel with U.S. Food and Drug Administration-approved formulations for use in both the brain and spine. Since its introduction in 2003, DuraSeal has been used in more than a million patients around the world. DuraSeal is distributed in more than 40 countries.
Integra LifeSciences is dedicated to limiting uncertainty for clinicians, so they can concentrate on providing the best patient care. Integra offers innovative solutions, including leading plastic and regenerative technologies, in specialty surgical solutions, orthopedics and tissue technologies.
Reference
1. Than KD, Baird CJ, Olivi A. Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery. Neurosurgery. 2008;63 (suppl 1):ONS182-ONS1. https://www.ncbi.nlm.nih.gov/pubmed/18728598).
Cerebrospinal fluid (CSF) leaks after posterior fossa surgery are a significant cause of longer hospital stays, hospital readmissions and other costly post-surgical interventions. This study demonstrated that the greater clinical effectiveness of Integra’s DuraSeal dural sealant at preventing CSF leaks compared to fibrin glue after posterior fossa surgery may help hospitals reduce costs.
The study, conducted by Dr. Marissa J. Carter, a renowned health economist, biostatistician, and clinical trial designer, confirmed a positive, consistent, cost-benefit that averaged $1,666 per patient for hospitals and surgeons who choose Integra’s DuraSeal dural sealant instead of fibrin glue. The study included 200 real-world patients in the United States who underwent posterior fossa neurosurgery.
The potential savings are based on the proven clinical efficacy of DuraSeal versus fibrin glue to reduce incisional cerebrospinal fluid leaks as found by Than et. al. in their independent clinical study, “Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery,” conducted at the Johns Hopkins University School of Medicine.1
“Integra understands that today’s healthcare providers must deliver the best treatment options to patients in a cost-effective way,” said Ajit Patwardhan, M.D., senior medical director, Integra LifeSciences. “Integra’s DuraSeal brand dural sealant is the only dural sealant indicated for dural closure with both clinical and economic evidence. This evidence makes DuraSeal the better clinical choice for surgeons and patients while also meeting the cost considerations of hospital administrators and operating room directors.”
Integra’s DuraSeal dural sealant is a polyethylene glycol hydrogel with U.S. Food and Drug Administration-approved formulations for use in both the brain and spine. Since its introduction in 2003, DuraSeal has been used in more than a million patients around the world. DuraSeal is distributed in more than 40 countries.
Integra LifeSciences is dedicated to limiting uncertainty for clinicians, so they can concentrate on providing the best patient care. Integra offers innovative solutions, including leading plastic and regenerative technologies, in specialty surgical solutions, orthopedics and tissue technologies.
Reference
1. Than KD, Baird CJ, Olivi A. Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery. Neurosurgery. 2008;63 (suppl 1):ONS182-ONS1. https://www.ncbi.nlm.nih.gov/pubmed/18728598).